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      community Anyone ever get a shedding phase on RU58441

      in Chat  6 upvotes 1 year ago
      The user experienced increased hair shedding after using RU58841 for two months, but found relief from scalp itchiness. Other users shared similar shedding experiences and discussed side effects like joint pain, while also mentioning the use of finasteride and minoxidil.
      Three weeks in and temples are responding

      community Three weeks in and temples are responding

      in Journals / Progress Pictures  35 upvotes 2 months ago
      The user reports improvement in temple hair after three weeks of using finasteride, minoxidil, ketoconazole, microneedling, stemoxydine, and follicopeptide. They note visible progress by maintaining the same hair length for comparison.

      community Had sides on finasteride ? A word of hope.

      in Finasteride  26 upvotes 8 years ago
      A user's experience with hair loss treatments, including finasteride and other options such as RU58841, Nizoral, Pumpkin Seed, and Adenosine; the importance of being in a positive frame of mind when considering taking finasteride; and the need to address life issues before starting finasteride.

      community hello

       144 upvotes 7 years ago
      A 12-year-old diagnosed with alopecia shares their experience and current treatments, including Dermovate, an unnamed cream, and liquid iron. The community offers support and encouragement.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Treatment isn't working? Stay the course.

      in Treatment  1 upvotes 1 year ago
      The user tried finasteride for a year without success, then switched to dutasteride and oral minoxidil for 10 months, still experiencing hair loss. Adding RU58841 and topical minoxidil seemed to improve their condition, with new hair growth observed.

      community Realistic expectations for my treatment

      in General  1 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The focus is on setting realistic expectations for these treatments.

      community Best solution for pyrilutamide in UK?

      in Treatment 2 years ago
      The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community 7 months Fin Treatment Progess

      in Progress Pictures  20 upvotes 9 months ago
      The user has been using finasteride, topical minoxidil, microneedling, red light therapy, ketoconazole shampoo, vitamin supplements, and scalp massages for hair loss since February 2025. They report stronger, thicker hair but are experiencing shedding and are considering increasing finasteride dosage or adding oral minoxidil.

      community Anyone with LPP have regrowth with Xeljanz?

      in Treatment  3 upvotes 1 year ago
      The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community Pyrilutamide 4 Month Journey with progress Pics..!!!

      in Progress Pictures  21 upvotes 10 months ago
      The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

      community Let's talk about Tsuji and Shiseido

       5 upvotes 7 years ago
      The conversation discusses hair loss treatments, focusing on Tsuji's hair cloning and Shiseido's RCH-01, with skepticism about their effectiveness on humans. It compares these to PRP, noting PRP's higher efficacy in studies.

      community Is S5 plus cream an okay alternative to finasteride?

      in Finasteride  4 upvotes 9 years ago
      The conversation discusses using S5 plus cream (Spironolactone, Alfatradiol, and Tempol) as an alternative to finasteride for hair loss, with concerns about its effectiveness and potential systemic absorption. The original poster already uses 5% minoxidil and is seeking alternatives due to fears of finasteride's side effects.

      community Tressless users finding the Scroll of Truth

      in Satire  131 upvotes 1 year ago
      The conversation humorously discusses hair loss treatments, focusing on the use of finasteride and dutasteride, with some users debating the effectiveness and cost of different dosages. Some users mention using topical minoxidil and express concerns about side effects and availability of higher doses.

      community Odds this guy is on dut? Im thinking 100%

      in Satire  29 upvotes 1 month ago
      The conversation discusses skepticism towards unconventional hair loss remedies, emphasizing the effectiveness of proven treatments like oral DHT blockers, topical minoxidil, and finasteride. It criticizes misleading advice and highlights the importance of starting effective treatments early.

      community Second shed and more abnormalities

      in Treatment  1 upvotes 1 year ago
      The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

      community GT20029 - Promising phase II results

      in Research/Science  15 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Killing the Norwood Reaper, a Journey

      in Progress Pictures  370 upvotes 2 years ago
      The user is treating hair loss with a regimen including Dutasteride, oral and topical Minoxidil, microneedling, and various supplements for overall health. They are considering adding tretinoin, stemoxydine/RU, DIM, Boron, and Fadogia Agretis to their routine.

      community My experience with Pyrilutamide

      in Update  43 upvotes 3 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community Sensitive to Oral fin + RU. Am I screwed?

      in Product  5 upvotes 4 years ago
      Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

      community Lets get this SHED baby - Buzzed and started fin/min

      in Progress Pictures  15 upvotes 3 months ago
      The user started using a hair loss treatment regimen including 5% minoxidil spray twice daily, 1% finasteride spray once daily, microneedling weekly, and ketoconazole shampoo twice a week, experiencing significant hair shedding. The shedding is seen as a positive sign, indicating hair follicles are entering a new growth phase.

      community Early Signs - Notes for diffuse thinners

      in Treatment  11 upvotes 4 months ago
      Diffuse thinning is often due to androgenetic alopecia, and DHT blockers like finasteride are recommended. Treatments mentioned include minoxidil, finasteride, dutasteride, and RU58841, with emphasis on starting early and using a holistic approach.

      community How well can HRT reduce scalp tension?

      in Transgender  4 upvotes 3 years ago
      A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.

      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  16 upvotes 2 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.