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      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 1 year ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community Upcoming and current hair growth stimulants (2026)

      in Research/Science  94 upvotes 4 months ago
      The conversation discusses various hair growth treatments, including topical and oral minoxidil, microneedling, LLLT, PRP, exosomes, latanoprost, copper peptides, and upcoming treatments like PP405 and Vdphl01. It also covers managing side effects of minoxidil, such as dry scalp, and mentions the use of dutasteride and finasteride for hair loss.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community New study on TOPICAL pumpkin seed oil in mice

       6 upvotes 6 years ago
      The conversation discusses a new study on topical pumpkin seed oil for hair loss in mice. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community i'm Considering adding hair stimulant: stemoxydine or alphatradiol

      in Treatment  5 upvotes 1 year ago
      The user is considering adding Stemoxydine to their hair loss regimen, as they already use topical finasteride with rosemary and cannot use Minoxidil. They are seeking feedback on Stemoxydine and Alphatradiol, and another user mentions 2-deoxy-d-ribose as a potential option.

      community Status update on upcoming treatments

      in Treatment  51 upvotes 1 year ago
      Current treatments like finasteride, minoxidil, and derma rolling are considered the best for hair loss, while new treatments such as GT20029, PP405, and others are in various trial phases with results expected in the coming years. There is cautious optimism about the affordability and effectiveness of these upcoming treatments.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Natural methods of reversing MPB

       5 upvotes 6 years ago
      The conversation discusses natural methods for addressing male pattern baldness, with the original poster using a plant-based diet, herbs, scalp massages, pumpkin seed oil, and dermapen treatments, while avoiding pharmaceuticals like minoxidil and finasteride due to concerns about side effects. Other users suggest that pharmaceuticals like finasteride may be necessary for significant hair loss, but the original poster remains committed to natural approaches.

      community What the hell happened in my family genes?

      in Chat  116 upvotes 2 years ago
      A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

      community Interpreting pre-finisteride blood panels

      in Chat  2 upvotes 1 year ago
      The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 1 year ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 2 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community Anyone heard of Exosome stem cell treatment?

      in Treatment  1 upvotes 1 year ago
      Exosome stem cell treatment for hair loss, which is expensive and reportedly effective, but its popularity has declined. The conversation also mentions Minoxidil, finasteride, and RU58841 as treatments.

      community Are all of these hair treatment companies the same?

      in Treatment  1 upvotes 10 months ago
      The user has been using topical finasteride and minoxidil since 2021 and is exploring other hair treatment companies like Xyon and Happy Head due to dissatisfaction with the current product's smell. They question the authenticity of consultations from these companies, suspecting they might be automated.