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      community Hot Take: Betting on PP405 can backfire

      in Research/Science  82 upvotes 9 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community 5mg oral minoxidil + 100mg Spironolactone

      in Progress Pictures  9 upvotes 2 years ago
      A user shared progress pictures using 5mg oral minoxidil and 100mg spironolactone, noting increased body hair and faster nail growth. Another user humorously suggested a new sub for people with similar experiences.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  260 upvotes 1 year ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community Can anyone else relate? M23. Pictures taken on the same day.

      in Styling  413 upvotes 1 year ago
      Hair looks thinner in sunlight, and users discuss using hair fibers, minoxidil, finasteride, and considering dutasteride for hair loss. Hair fibers like Toppik help conceal thinning, and some users suggest additional treatments like derma stamping and micro-needling.

      community minoxidil scalp Inflammation, lossing my hair very fast,

      in Minoxidil  5 upvotes 3 years ago
      The user experienced scalp inflammation and rapid hair loss after using minoxidil, despite initial success. Suggestions included switching to minoxidil foam, using oils, trying aspirin, and considering RU58841 for inflammation and hair loss management.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 2 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community 10 months of minoxidil + cheating

      in Transgender  180 upvotes 11 months ago
      A user shared their positive experience with hair regrowth using minoxidil, hormone replacement therapy, and cyproterone acetate during their male-to-female transition. Another user discussed their successful hair transplant after transitioning and using finasteride, highlighting the challenges of hair loss and regrowth during transition.

      community 32, Southeast Asian, 1 y 3 m Finasteride, Dutasteride, Minoxidil, Microneedling – Former hair system user. Quick description of routine in comments.

      in Progress Pictures  324 upvotes 3 years ago
      A user named "bmbshell" who was dealing with hair loss and initially tried to fix it with a hair system before deciding to try finasteride, dutasteride, minoxidil, microneedling, and biotin supplements. They documented their progress over the past 1 year and 3 months, showing how effective these treatments were in regrowing their hair.

      community 32M, 5 year progress pictures

      in Journals / Progress Pictures  250 upvotes 1 year ago
      The user has been using finasteride, ketoconazole shampoo, oral minoxidil, and minoxidil foam for hair loss but feels their hair is not as thick as desired. They have stopped using RU58841 due to lack of results and are concerned about hair miniaturization despite these treatments.

      community 8 months progress on fin + min

      in Progress Pictures  150 upvotes 2 years ago
      The user "Dame2Miami" shared their 8-month progress using finasteride and minoxidil for hair loss. Other users commented on their impressive gains and expressed support.

      community 5.5 months on Minoxfin (*Ideal Situation)

      in Progress Pictures  26 upvotes 1 month ago
      A 22-year-old user shared progress pictures after 5.5 months of using a topical solution containing Minoxidil and Finasteride for hair loss, noting increased hair density and reduced hair fall despite inconsistent application. The user recently switched to oral Dutasteride and Minoxidil due to difficulty with topical solutions and plans to update after a year.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 3 years ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

      community 23m asian progress - minoxidil + micro + vitamin

      in Progress Pictures  38 upvotes 2 years ago
      A 23-year-old Asian male shared progress pictures after 3 months of using minoxidil, microneedling for 1.5 years, and taking vitamin supplements. Replies suggest adding finasteride or dutasteride for long-term hair maintenance.

      community Regimen proposal (incl. dut meso) (event industry)

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community 5 months of nuking T, 2 months of minoxidil

      in Transgender  487 upvotes 1 year ago
      The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

      community 3 month progress | Minoxidil once a day

      in Progress Pictures  190 upvotes 1 year ago
      The user experienced severe side effects from finasteride and switched to using minoxidil and a derma stamp, seeing positive hair regrowth after initial shedding. They are considering topical finasteride to avoid side effects while maintaining hair health.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 8 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 3 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.