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      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 1 year ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community 14 Months Dut/Minox/Microneedling + 13 Months HRT

      in Transgender  36 upvotes 2 months ago
      The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.

      community PP405 Phase 2a press release with early results

      in Research/Science  700 upvotes 1 year ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Can RU58841 stop hairloss for a long time?

      in Research/Science  9 upvotes 2 years ago
      A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

      community 18M progression pt.3 (6 months)

      in Progress Pictures  744 upvotes 3 years ago
      User started balding at 16 and began treatment at 18, using RU58841, minoxidil, derma rolling, and peptides. After 6 months, they experienced significant hair regrowth and are happy with the results.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 4 months ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  21 upvotes 1 year ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community Thoughts on Bryan Johnson’s new hair loss product?

      in Product  143 upvotes 9 months ago
      Bryan Johnson's new hair loss product, which includes peptides, is viewed skeptically by many, with concerns it may be a money grab rather than an effective treatment. Most users prefer proven treatments like finasteride and minoxidil, which are cheaper and have established results.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community What’s more reliable right now, pyrilutamide or RU?

      in Treatment  15 upvotes 3 years ago
      Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

      community RT1640 - Gray Hair Reversal Recipe

      in Research/Science  3 upvotes 3 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

      community It's always the Mice that gets to grow back hair.

      in Research/Science  431 upvotes 7 months ago
      Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

      community Shedding and thinning won’t stop on Nuclear protocol

      in Treatment  18 upvotes 2 years ago
      The user is using a combination of hair loss treatments including dutasteride, minoxidil, RU58841, low-level laser therapy, ketokonozole, supplements, Viviscal, Nutrafol, microneedling, PRP, and scalp Botox injections, but is still experiencing hair shedding and thinning. Despite being on this regimen for two years, the user's hair condition is worsening, and they are seeking advice on what else they can do.

      community TresslessGPT is available to ChatGPT Plus users

      in 📣 Announcement  107 upvotes 2 years ago
      The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Do these two supplements inhibit 5alpha-reductase?

      in Chat  1 upvotes 5 years ago
      Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.

      community What microneedling regiment worked for you?

      in Microneedling  8 upvotes 6 months ago
      Microneedling regimens for hair loss, with users discussing needle lengths and frequencies. One user reports noticeable improvement at the crown using 1mm weekly, while another uses Keto shampoo with dermastamping.

      community Exosomes therapy -- any personal experience?

      in Treatment  3 upvotes 1 year ago
      Exosome therapy for hair loss is being discussed, with mixed personal experiences and no significant results reported by some users. The treatment is expensive, and users are skeptical about its effectiveness.