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      community The story of RU58841/PSK3841

      in Research/Science 2 years ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Minokem-N cotains hydrocortisone?

      in Minoxidil  2 upvotes 1 year ago
      Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

      community Has anyone tried/made a sulforaphane topical?

      in Treatment  4 upvotes 4 years ago
      The conversation discusses the potential of creating a homemade sulforaphane topical for hair loss treatment. Participants mention challenges with sulforaphane stability and reference other treatments like Minoxidil.

      community 8-months progress: dermarolling + supplements

      in Progress Pictures  261 upvotes 2 years ago
      A user shared an 8-month hair loss treatment progress using daily saw palmetto and biotin capsules, weekly dermarolling, and a scalp lotion mix of castor, jojoba, and rosemary oils, avoiding finasteride and minoxidil due to side effects and cost. The user reported encouraging progress with slight hairline improvement and better crown area, attributing most success to dermarolling.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community ru58841 in europe, without getting water in the mail.

      in Product  1 upvotes 5 months ago
      The conversation is about finding a trustworthy and affordable source for RU58841 in Europe, with a comparison between Anagenic and Actifolic. The user seeks experiences from others in the EU to avoid receiving water instead of the product.

      community Where can I get this topical solution compounded?

      in Treatment  1 upvotes 5 months ago
      A user is seeking a pharmacy to compound a topical solution containing Minoxidil, Finasteride, Alfatradiol, Melatonin, Latanoprost, and either RU58841 or Pyrilutamide. They prefer a professional compounding lab over DIY methods.

      community The use of peptides to enhance hair growth from wounding

       4 upvotes 9 years ago
      The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.

      community Quercetin got rid of my scalp soreness

      in Chat  4 upvotes 1 year ago
      Quercetin reduced scalp soreness and may help with histamine-related hair loss. The soreness felt like inflamed follicles beneath the scalp surface.

      community At what dose did Spironolactone really start working?

      in Female  2 upvotes 2 years ago
      A user is asking women with androgenic alopecia about the effective dose of spironolactone for hair regrowth, mentioning they've been on 100 mg for a year with minimal results and considering increasing the dose. The conversation focuses on the effectiveness of spironolactone for hair loss treatment.

      community Minoxidil+ Spray by keep does it contain propylene glycol?

      in Minoxidil  1 upvotes 1 year ago
      The user is using Dutasteride and oral Minoxidil for hair regrowth and is considering adding topical Minoxidil but is allergic to propylene glycol, which is present in the product they found. They need a solution with tretinoin that does not contain propylene glycol.

      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 6 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community I tried salt water to stop the DHT itch

      in Treatment  59 upvotes 3 years ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community RU58841 from china... Which supplier?

      in Product  6 upvotes 2 years ago
      The conversation is about the quality of RU58841 powder from Shaanxi Laon Biotech. The user is inquiring if anyone has experience with this product.

      community Growth Stimulants that aren't Minoxidil...?

      in Research/Science  8 upvotes 2 years ago
      The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.

      community Castor Oil + Coconut Oil + Derma Rolling

      in Treatment  7 upvotes 8 years ago
      A user is experiencing temple hair recession and is seeking alternatives to finasteride. They are considering castor oil, coconut oil, and derma rolling, and have seen some improvement with Zenegen.

      community Ru with gloves because of Systemic absorption?

      in Research/Science  10 upvotes 2 years ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

      community Homemade pyri solution- problems

      in Treatment  1 upvotes 2 years ago
      A user mixed a pyrilutamide solution and noticed undissolved powder at the bottom, questioning if this is normal and how long to wait before applying it. They wished others good luck with their treatments.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Correct proportion of topical oils - castor, rosemary, peppermint

      in Treatment  7 upvotes 2 years ago
      The conversation is about finding the correct proportions of topical oils for hair loss treatment. The proposed mixture includes 10ml castor oil, 2ml rosemary essential oil, 1ml peppermint essential oil, and 1ml tea tree essential oil, applied three times weekly.