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      community Nutrafol backed by Science to reverse male balding?

      in Research/Science  1 upvotes 1 year ago
      Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 year ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 6 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community RU58841 in powder form from Aliexpress. Is this safe to purchase?

      in Product  3 upvotes 2 years ago
      A user is considering buying RU58841 powder from Aliexpress to mix with Minoxidil for hair loss treatment. Another user warns about the safety concerns of RU58841, especially from unreliable sources, and suggests trying finasteride, oral Minoxidil, and dutasteride first.

      community Finasteride Concerns: Nipple Sensitivity and Gyno Risk at 23M

      in Basic Questions  117 upvotes 1 month ago
      A 23-year-old male experienced nipple sensitivity after starting finasteride for hair loss and stopped using it due to concerns about gynecomastia. He is worried about the risk of developing gynecomastia if he resumes finasteride, especially with plans to increase muscle mass.

      community RU58841 and some major questions?

      in Treatment  7 upvotes 2 years ago
      A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

      community GT20029 Big Phase 2 Update Results!

      in Research/Science  53 upvotes 8 months ago
      GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

      community a new supplement just released

       11 upvotes 8 years ago
      A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

      community Finasteride Watery Semen

      in Finasteride/Dutasteride  3 upvotes 6 years ago
      A user noticed watery semen and decreased volume after a week of using finasteride and asked if taking Zinc, pygeum, and lecithin supplements would affect finasteride's effectiveness. The conversation is about the side effects of finasteride and potential supplements to counteract them.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 9 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community questions regarding topical finasteride

      in Finasteride  4 upvotes 7 years ago
      The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 3 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Anyone else just waiting until the real pyrilutamide and then GT20029?

      in Chat  4 upvotes 2 years ago
      The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

      community Update and new paper from Dr tsuji

      in Update  26 upvotes 7 years ago
      Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

      community Finasteride is love, Finasteride is life

      in Finasteride/Dutasteride  35 upvotes 4 years ago
      The positive effects of taking finasteride for hair loss, with the poster being four months into treatment and seeing improved thickness on their right side of scalp. Another user replied expressing hope in having similar results after starting to take finasteride.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 1 year ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community How is this looking on around day 80 and question

      in Progress Pictures  2 upvotes 6 months ago
      The user is experiencing negative side effects from a hair loss treatment containing finasteride and minoxidil due to high vitamin B6 content and plans to switch to separate pills without unnecessary vitamins. Another user suggests using a version without B6, noting similar symptoms from finasteride.

      community Roughly one year on finasteride

      in Progress Pictures  513 upvotes 2 years ago
      The conversation is about someone's positive experience with 0.5 mg of finasteride daily for hair loss, noting potential contributions from vitamins and health improvements. Side effects and observations from others include watery semen and questions about hair regrowth and shedding phases.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 7 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.

      community Has anyone tried combining Minoxidil with AlphaInfuse?

      in Is this regrowth?  2 upvotes 11 months ago
      The conversation discusses the use of AlphaInfuse, a micro-infusion system with Panax ginseng and Eclipta prostrata extracts, for hair growth and its comparison to Minoxidil. The original poster seeks personal experiences and evidence of its effectiveness.