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PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.

Pelage received $120 million for phase 3 of PP405, a potential hair loss treatment, but there is skepticism about its success. Some users believe any improvement over finasteride is a win, while others expect full hair regrowth.

The user experienced significant hair regrowth and improved hair volume after 4 months of using oral dutasteride (0.5 mg) and minoxidil (2.5 mg) daily, eliminating the need for a second hair transplant. The user is now satisfied with the results and feels more confident.

The user reported progress in hair regrowth after 3 months using finasteride, biotin, and minoxidil, with no sexual side effects. Most responses noted significant improvement, encouraging continued use for full results.

A user shared their positive 3-month results using a treatment for hair loss that includes Dermaroller, Minoxidil, and Amplexe Shampoo. They avoided using finasteride due to its risks.

A user with diffuse thinning, currently using finasteride, biotin, minoxidil, and nizoral shampoo, is considering a topical solution called "82M" but is skeptical due to its high cost and lack of supporting research. They seek others' experiences with "82M."

The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.

The user has been using minoxidil and dermarolling for 9 months and saw palmetto for 2 weeks to address female pattern baldness with vertex balding. They are seeking feedback on any progress in hair regrowth.

The user shared a 4-5 month update on using finasteride, minoxidil, vitamins, oiling, and microneedling for hair loss. They reported improved hair density and confidence but experienced unwanted hair growth, thin hair, itching, and a flaky scalp.

The user is currently using finasteride and minoxidil and is considering adding microneedling and either RU58841 or Pyrilutamide for potential hair regrowth. They previously used microneedling, RU58841, and oral minoxidil before their hair transplant.

A user is concerned about hair loss in the temple area despite using Minoxidil and finasteride for 10 months and is curious if PP405 can help. Responses indicate uncertainty about PP405's effectiveness, with some optimism about future treatments and AI speeding up drug discovery, but emphasize waiting for clinical trial results.

The user resumed using topical finasteride after a two-week break and will update on side effects like water retention and gynecomastia in a month. They are also starting DIM and zinc.

A user shared progress pictures after 50 days of using a compound with 10% minoxidil, 0.1% finasteride, and biotin, expressing satisfaction with the results. Another user commented positively on the progress.

A dermatologist recommended PRP (Platelet Rich Plasma) and GFC (Growth Factor Concentrate) for pattern baldness, but online sources suggest they may not be effective. The user is seeking opinions on these treatments.

User is a Norwood 2-2.5, using 1.25 mg finasteride and 5% minoxidil lotion daily since June last year, experiencing significant regrowth. They are considering additional treatments like saw palmetto, microneedling, dutasteride, aminexil, stemoxydine, mesotherapy, ketoconazole shampoo, and alfatradiol to improve hair thickness.

A 26 year old female diagnosed with androgenetic alopecia who is interested in treatments such as spironolactone, finasteride and Minoxidil to help her hair loss but is worried about side effects like muscle gain, sex drive and effectiveness.

Minoxidil can be used with isopropyl alcohol to create topical spironolactone. Spironolactone may dissolve better in ethanol or propylene glycol.

The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

A user reported positive hair regrowth using finasteride and minoxidil for 2 months, noting thicker roots and improved appearance. The post led to skepticism and discussions on treatment methods and side effects.

The user noticed baby hair growth and thicker hair after using minoxidil, rosemary, and a dermaroller for two months and plans to start finasteride soon. Another user suggests cutting hair to the same length for better comparison.

The user experienced hair regrowth after 10 months using Minoxidil, 2.5 mg Dutasteride, and 0.5 mg Finasteride. They switched from a compounded pill to Avodart capsules and plan to reassess their treatment after one year.

The user shared their 8-week hair regrowth progress using 0.5mg dutasteride, twice-daily topical minoxidil, and weekly 1.5mm microneedling. They noted visible improvement, though some users suggested reducing microneedling depth to avoid potential scalp damage.

A 21-year-old has been using oral finasteride, topical minoxidil, and tretinoin for 2 months and notices potential regrowth with baby hairs. They consider adding dutasteride weekly but wonder if current treatments are sufficient.

Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.

The user is generally happy with their hair transplant results but has concerns about graft density and placement, particularly on the left temple and hairline. They are using finasteride and minoxidil inconsistently, plan to add Priorin, and are considering microneedling and PRP sessions for future care.

The conversation discusses DIY cosmetic procedures like PRP, mesotherapy, and micro-needling, with some users experimenting with Minoxidil, finasteride, and RU58841 for hair loss. It highlights a community of mostly older women performing these treatments themselves.

The conversation discusses potential hair loss treatments, including hair cloning, setipiprant, and topical finasteride, questioning their availability and effectiveness as permanent cures. The user is inquiring about the release dates and efficacy of these treatments.

The conversation discusses the differences between PG/Ethanol and KB solutions for RU58841 application, focusing on potential scalp irritation. KB solution is suggested for those allergic to PG, though both contain ethanol which can dry the scalp.

A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.

The conversation discusses hair loss treatments, specifically increasing the dose of dutasteride from 0.5 to 2.5 mg, and the resulting hair shedding. Users share mixed experiences, with some seeing improvement after shedding and others finding higher doses less effective.