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      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 7 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community 6 Month Update - (3 Month of Finasteride)

      in Progress Pictures  423 upvotes 11 months ago
      The user experienced positive hair regrowth after 6 months of treatment, using topical minoxidil and finasteride, with no significant side effects. They also improved their diet and exercise routine, and are considering dermarolling if progress stalls.

      community SUBE3 for sale in the gray market?

      in Chat  4 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community I think Progress 6 months mark what do you think guys

      in Progress Pictures  123 upvotes 1 year ago
      The user experienced significant hair regrowth and reduced shedding after using finasteride, dutasteride, and topical minoxidil for six months, with no major side effects. The user emphasizes the importance of tracking progress and plans to continue the treatment indefinitely.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 11 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community DS Labs SOD suppliments, anyone try them?

      in Product  4 upvotes 1 year ago
      The conversation is about trying DS Labs SOD supplements for hair loss, which contain ingredients like Genistein, B-sitosterol, and Biotin. The user is considering adding these supplements to their existing hair care routine.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  460 upvotes 9 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Has anyone gotten pp405 on the grey market yet?

      in Research/Science  10 upvotes 2 months ago
      People are discussing the use of an untested hair loss treatment called PP405, which is not available on the grey market. Some users are trying a mimic formulation called HP3, reporting thicker hair but no new growth yet.

      community 6 MONTHS PROGRESS (HAIR TRANSPLANT)

      in Update  24 upvotes 1 month ago
      The user shared a 6-month update on their hair transplant progress, noting they still use oral minoxidil and dutasteride daily. They are pleased with the results but observe increased hair shedding during showers.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 5 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community M46 - 3 week progress on HIMS serum

      in Progress Pictures  12 upvotes 2 years ago
      A 46-year-old male shared his 3-week progress using HIMS serum with Finasteride 0.3% and Minoxidil 6%, showing improvement without noticeable shedding. His routine includes vitamins, a healthy diet, and specific hair care practices like microneedling and using caffeine solution.

      community Possibility of updates or more information on the pp405

      in Chat  19 upvotes 7 months ago
      The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

      in Research/Science  57 upvotes 11 months ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community MY 6 MONTH TRANSFORMATION PROGRESS

      in Progress Pictures  210 upvotes 1 year ago
      A 23-year-old male shared his 6-month hair transformation using Dutasteride, oral Minoxidil, ketoconazole shampoo, vitamin D, gym, cardio, and dermastamping. He reported significant hair maintenance and no side effects.

      community 6 month update - 3200 FUE grafts, oral fin/min, keto shampoo, biotin

      in Progress Pictures  300 upvotes 2 years ago
      A user shared their 6-month hair loss treatment progress, which included 3200 FUE grafts, oral finasteride and minoxidil, keto shampoo, and biotin. The user also mentioned micro needling their temples for further growth and plans to observe the effects of finasteride and minoxidil over the next 6-12 months.

      community 6 months in: Possible changes to treatment plan

      in Treatment  1 upvotes 1 year ago
      A 21-year-old male has been on a hair loss treatment for 6 months using finasteride, oral minoxidil, and ketoconazole shampoo, with slight improvement noted by his dermatologist. He is considering adding topical spironolactone, switching to dutasteride, increasing minoxidil dosage, or trying PRP injections for better results.

      community ASCEplus HRLV Exosomes with microneedling

      in Product  1 upvotes 2 years ago
      The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

      community 1064 Grafts, Pre to Mo 8.5, Kaan Pekiner

      in Update  309 upvotes 1 year ago
      A user shared an 8.5-month update on their hair transplant of 1064 grafts done by Dr. Kaan Pekiner in Ankara, Turkey, costing $3500. They are also using finasteride 2.25 mg weekly and have reduced shampoo use.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.