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390-420 / 1000+ resultscommunity Binding affinity of pyrilutamide!
Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.
community Irritation from topical min (maybe propylene glycol)
User experienced scalp irritation from Kirkland 5% liquid minoxidil, likely due to propylene glycol. They are seeking non-PG liquid alternatives that are affordable.
community 3 months of progress on 5% foam minoxidil and .3% dutasteride.
The user shared progress pictures showing significant hair regrowth after three months using 5% foam minoxidil, 0.3% dutasteride, microneedling, pumpkin seed oil, and rosemary oil. The user reported no side effects and chose topical treatments to avoid them.
community Doctor prescribed me with topical min but no fin. i also have sebderm. should i go to another doctor?
The user is concerned about using only minoxidil for hair loss without finasteride, despite having seborrheic dermatitis. They are considering seeking a second opinion from another doctor.
community Would appreciate some thoughts on the “dht itch”
The user is experiencing scalp itching despite using finasteride and Ketoconazole shampoo for hair loss and seborrheic dermatitis. They are unsure if the itch is due to their treatments, diet, or mental factors.
community Burning/itching sensation & terrible tenderness on scalp accompanied with heavy shedding
The user is experiencing increased hair shedding, scalp sensitivity, and itching despite using finasteride for four months, and has tried various shampoos without relief. They are advised to consult a dermatologist for potential scarring alopecia and consider other treatments like adding Dutasteride.
community 7 month update (Dut 0.5 daily, topical min 5% twice a day - 5.5 months, microneedling 3 months)
The user experienced significant hair regrowth using dutasteride 0.5 mg daily, 5% topical minoxidil twice a day, and microneedling over several months. They also used ketoconazole shampoo and rosemary oil, reporting some side effects but overall positive results.
community Topical Dutasteride Recommended doses and concentrations with microneedling?
Topical dutasteride with microneedling is effective for androgenetic alopecia, improving hair thickness and density. Further research is needed to confirm long-term efficacy.
community 6 months fin, min, dermastamp, RLT
The user has been using finasteride, minoxidil, a dermastamp, and red light therapy for six months with no visible improvement since the three-month mark. Other users noted improvement, particularly in the left temple area, and encouraged the user to continue.
community Choose your topical antiandrogen and tell me why
The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.
community kx826 .05% month 8 | topical minoxidil .5% month 21 combo update.
The user used finasteride but stopped due to side effects, then used topical minoxidil for 13 months, and later added KX826/pyrilutamide for 8 months. They experienced shedding after starting pyrilutamide and use minoxidil and KX826 once daily.
community M22 Almost 3 months into treatment
A user shared progress pictures after almost 3 months of using dutasteride, minoxidil, stemoxydine, and tretinoin for hair loss, reporting positive results and no significant side effects. The user chose dutasteride over finasteride due to early balding and noted benefits like better skin and increased libido.
community ~3,5months progress on topical minoxidil, ketoconazol and dermarolling
The user shared their 3.5-month progress using topical minoxidil, ketoconazole shampoo, and dermarolling for hair loss, and plans to start finasteride. They experienced relief from scalp issues with ketoconazole and are managing side effects from minoxidil.
community 3 years of treatment Dut, topical Min, 1 year of RU
community 3 months on topical fin/min/stamping
The user has been using a topical combination of finasteride, minoxidil, and dermastamping for three months to address hair loss. They are considering adding tretinoin and are discussing the effectiveness of topical versus oral treatments.
community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively
Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.
community Has anyone tried 2% Pyrilutamide from Anagenica?
The conversation discusses using 2% Pyrilutamide from Anagenica for hair loss, as the user did not see results with 1% Pyrilutamide. The user is considering increasing the dosage but is concerned about the cost.
community Bumps After 1 Month of Weekly Microneedling at 1mm
Microneedling once a week at 1mm caused bumps, possibly scars, in the treated area. The user is considering cleaning the skin before microneedling to prevent this issue.
community Pelage Pharmaceuticals with an absolute stunner of a molecule
PP405 is a promising new treatment for hair loss. It performs three actions in one, potentially offering a cure.
community Why is there so much negativity around pyrilutamide?
Pyrilutamide is discussed as an effective hair loss treatment by some users, despite skepticism due to limited data and underwhelming trial results. Users compare it to finasteride, minoxidil, and RU58841, with some expressing interest in its potential as an adjunct treatment.
community New baby hairs are popping out. Question though: what are these black dots on hairline? Clogged pores?
The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.
community Macro photos of progress - dutasteride + topical minoxidil : 3,5 months
A 30-year-old male with androgenic alopecia shows progress after using dutasteride (0.5 mg daily) and topical minoxidil (5% twice daily) for 3.5 months. Users suggest adding dermastamping for better results.
community Feeling A LOT of stubble on my scalp (I'm a diffuse thinner). What does this mean?
A user with diffuse thinning noticed stubble-like hairs on their scalp after using 2% ketoconazole shampoo, dermarolling, castor oil, Vitamin D3, biotin, and iron supplements. They are unsure if this indicates regrowth or miniaturized hairs.
community Thank you Min, Ket, and Dermastamping! (19 M)
A user shared progress pictures showing hair improvement after using Minoxidil Foam, Nizoral Shampoo, and microneedling. They plan to add finasteride in a few months.
community Can rosemary oil cause gynaecomastia?
A user is concerned that using rosemary oil after microneedling might cause gynaecomastia due to increased absorption and potential DHT blocking. Other users believe rosemary oil is unlikely to affect hormones or cause gynaecomastia.
community For those that want to try the cosmetic pyrilutamide, I have a Chinese contact
The conversation is about obtaining pyrilutamide for hair loss treatment from China through a contact, with details on pricing and shipping. The user offers to facilitate the purchase and shipment for a small commission.
community Pelage are starting phase 3 for PP405 towards the end of 2026
PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.
community Current progress pics and is there anything i should change in my routine
The user is using topical finasteride 0.1%, minoxidil 5% twice daily, red light therapy, a multi-peptide serum, and a weekly oil hair mask with various oils and ingredients. They also use ketoconazole shampoo, condition their hair, and microneedle with a dermapen, seeking advice on any changes to their routine.
community Foligain foam & scalp problems
Foligain foam caused severe scalp irritation and flakiness, unlike Rogaine foam. The user plans to consult a dermatologist for treatment options.