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      community 21 M - 6 months on 1mg Finasteride every day

      in Progress Pictures  120 upvotes 2 weeks ago
      A 21-year-old male shared progress pictures after 6 months of using 1mg finasteride daily, reporting no side effects and noticeable improvement. The user got finasteride prescribed and did not mention using it in combination with minoxidil.

      community A Short Recap on PP405 and AAD 2026

      in Update 3 weeks ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Dear tressless, i have a question for you.

      in Technology  452 upvotes 3 weeks ago
      Minoxidil and finasteride are discussed for hair loss, with concerns about minoxidil's heart-related side effects. New treatments like PP405 are met with skepticism, often humorously noted as always being "five years away."

      community Found a slide summary for PP405

      in Research/Science  36 upvotes 3 weeks ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community Is it possible for diffuse thinning to stop or retard?

      in Finasteride/Dutasteride  11 upvotes 1 month ago
      Diffuse thinning is unpredictable, and while some suggest treatments like finasteride or dutasteride, others emphasize acceptance as hair loss may continue. Some users share personal experiences with treatments like nizoral, scalp massage, and lifestyle changes, but results vary.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 1 month ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community 2 MONTHS ALL NATURAL HAIR REGROWTH REGIMEN & RESULTS

      in Is this regrowth? 1 month ago
      The conversation discusses using natural products like rosemary, tea tree, and aloe, along with a DIY coffee rinse to block DHT for hair regrowth, avoiding minoxidil and finasteride. Some users express skepticism about the effectiveness of natural remedies compared to conventional treatments.

      community Switching to a more aggressive stack

      in Progress Pictures  4 upvotes 1 month ago
      The conversation is about a user switching to a more aggressive hair loss treatment, adding dutasteride 0.5mg and oral minoxidil 2.5mg to their current regimen of finasteride 0.02%, minoxidil 5%, biotin, massages, and microneedling. Users suggest increasing finasteride dosage and caution about potential side effects of oral minoxidil.

      community Losing my hair since 18, feel like a monster

      in Chat  36 upvotes 1 month ago
      A 21-year-old is experiencing severe hair loss despite using finasteride and minoxidil, and plans to try dutasteride. Others share similar struggles and suggest various treatments like RU58841, spironolactone, and hair systems, while emphasizing the emotional impact of hair loss.

      community 7.5 Months on Min + Fin — Progress Pics + Questions (Crown, Temples, Folliculitis)

      in Is this regrowth?  76 upvotes 1 month ago
      The user has been using minoxidil and finasteride for 7.5 months to address hair thinning, particularly at the crown and temples, and is considering additional treatments like tretinoin and dermastamping despite having chronic scalp folliculitis. They are experiencing progress but are concerned about side effects and the effectiveness of treatments on temple regrowth.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 1 month ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community Is sustained Finasteride use safe?

      in Finasteride/Dutasteride  5 upvotes 1 month ago
      A 28-year-old experienced hair loss and found success with daily 1mg Finasteride, noticing thicker hair without side effects. Despite this, their dermatologist suggested switching to expensive peptide serums, prompting the individual to seek a second opinion on long-term Finasteride and oral Minoxidil use.

      community Dutasteride + Minoxidil oral results - 6/7 months

      in Is this regrowth?  30 upvotes 1 month ago
      The user experienced hair regrowth using oral Dutasteride and Minoxidil over 6-7 months, despite some ongoing hair shedding. They reported no significant side effects, although some users discussed potential brain fog and cognitive issues possibly linked to Dutasteride.

      community I wish I were a man so bad. Life is cruel

      in Female  227 upvotes 1 month ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community Does This Invalidate PP405 Completely?

      in Research/Science 1 month ago
      PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.

      community I'm very skeptical about pyrilutamide

      in Product  2 upvotes 2 months ago
      Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 2 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community 138 days os scalp massaging!! Update!!!

      in Chat  6 upvotes 2 months ago
      Scalp massaging for hair loss hasn't shown significant changes yet, but the scalp is more flexible. Combining treatments like minoxidil, tretinoin, dutasteride, inversion, microneedling, and a good diet might enhance results.

      community Six months on min/fin + supplement chews

      in Progress Pictures  12 upvotes 2 months ago
      A 49-year-old is using minoxidil, finasteride, and supplement chews for hair growth, experiencing thick growth except on the top, and seeking advice on improving density. Suggestions include continuing treatment, considering additional options like oral minoxidil, ketoconazole shampoo, dermapen, and possibly a hair transplant, though cost is a concern.

      community Will Pp405 be the Ozempic of bald Guys

      in Research/Science  103 upvotes 2 months ago
      PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

      community Before and after of 20 months of fin and min

      in Progress Pictures  125 upvotes 2 months ago
      The user experienced worsening hair thinning despite using finasteride, minoxidil, and ketoconazole shampoo, and switched to dutasteride five months ago. They are considering adding tretinoin and microneedling to their routine for better results.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 2 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community What I've learned from being on treatment after 18 months

      in Chat  33 upvotes 2 months ago
      Patience and consistent use of treatments like Dutasteride and oral Minoxidil are key for hair regrowth, with noticeable improvements often taking around 10 months. Maintaining scalp health with products like ketoconazole shampoo and conditioners is also important for effective treatment.