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      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  132 upvotes 1 year ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community Ru vendor? Looking for a cheaper source

      in Product  3 upvotes 1 year ago
      The conversation is about finding a cheaper source for RU58841, with a suggestion to use Chemyo. One user suggests that RU58841 may not be necessary.

      community Alfatradiol 0.1% anyone know a source?

      in Treatment  3 upvotes 1 year ago
      The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

      community Is this hierarchy of topical anti androgens accurate?

      in Ketoconazole  7 upvotes 4 years ago
      User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Low Estradiol while on 1mg Fin, what should I do?

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.

      community Adding topical dutasteride to my stack

      in Treatment  5 upvotes 2 years ago
      A 38-year-old woman has been using oral Dutasteride for a year without improvement and is now adding a topical solution containing Minoxidil, Dutasteride, Tretinoin, Ketoconazole, and Hydrocortisone. She is seeking advice on whether switching from oral to topical Dutasteride could prevent hair shedding.

      community hight pre-finasteride estrogen levels

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      A user with high pre-finasteride estrogen levels is asking if they need to normalize their hormone levels before starting finasteride and whether they should postpone dermarolling until they begin finasteride. The user is 21.5 years old.

      community Clascoterone/ Breezula will it work

      in Research/Science 2 months ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

      community Help On Topical Finasteride 0.3%

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      A user is seeking advice on a new topical hair loss treatment containing Minoxidil 3%, Finasteride 0.3%, Progesterone 1%, Hydrocortisone butyrate 0.1%, and Ketoconazole 0.5%. They are concerned about the systemic absorption of Finasteride and plan to do blood tests and a spermiogram before starting.

      community Is my current doseage viable? (Trans)

      in Transgender  3 upvotes 7 months ago
      The user is taking Dutasteride, Finasteride, Estradiol, Spironolactone, and Progesterone for hair regrowth and is considering adding Minoxidil and rosemary oil. They are experiencing some hair regrowth and are consulting a dermatologist to avoid a hair transplant.

      community Thoughts on Pantostin Alfatradiol?

      in Treatment  10 upvotes 4 years ago
      User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

      community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 5 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.
      Any experiences with fin/dut alternatives?

      community Any experiences with fin/dut alternatives?

      in General  76 upvotes 11 months ago
      The user is exploring alternatives to finasteride and dutasteride due to concerns about side effects, and is using rosemary and jojoba oil, ketoconazole, minoxidil, microneedling, multi-peptide serum, saw palmetto, and stinging nettle for hair loss. They are also considering CB 03 01 and spironolactone.

      community Estrogen lowering supplements while on Finasteride?

      in Treatment  8 upvotes 4 years ago
      The conversation discusses using aromatase inhibiting supplements like DIM and Grape Seed extract while on finasteride for hair loss treatment. Users share their experiences and opinions on combining these supplements with finasteride.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 1 year ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.