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120-150 / 1000+ resultscommunity Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in
community Advanced AGA and DUPA at 25. Starting Nuclear Stack: Day 178 (6 months-ish)
A user is treating hair loss with Dutasteride, Minoxidil, RU58841, Derminator 2, Vitamin D, Biotin, and Zinc. After 6 months, there's no significant visual improvement, but the user feels less insecure about Retrograde Alopecia.
community Progress: 6 months 1.5 Fin - 1month 3.5 MIN and 0.5 DUT
community How hard does RU58841 powder degrade with time?
RU58841 powder may degrade over time, even when stored in a freezer. Users discuss its potential effectiveness after three years of storage.
community Curious about 'nuclear' stacks
The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.
community Help me interpret my bloods
The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.
community post transplant / post finasteride
community From June 22 to August 23 slowww progress
The conversation is about a person's slow progress in treating hair loss using finasteride, microneedling, testosterone replacement therapy, dutasteride, RU58841, and minoxidil. They experienced a significant hair shed after adding dutasteride.
community Clascoterone full results in July
Clascoterone's full trial results are expected by mid-July 2026, but skepticism exists about timely release. Clascoterone is available at 5% from some telehealth companies.
community 1 year long Dutasteride shed finally working itself out
community 26 M Before, Mid, After 13 Months
community 3 months progress picture 18m 1mg fin daily
community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
community Age 22 .2nd month on finestride
A 22-year-old is experiencing increased hair shedding and a greasy scalp after two months on 1mg finasteride. They are documenting their progress and seeking advice, with feedback suggesting that shedding is normal and results may take 6-12 months.
community 5ARI (dutasteride) Associated with Adverse Metabolic Effects
Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.
community Can gains from stemoxydine be permanently kept with 5AR inhibitors?
Stemoxydine's effects on hair growth are uncertain and not well-studied, with users reporting mixed results and concerns about maintaining gains. Some users combine it with 5AR inhibitors like Dutasteride, but results vary, and conditions like lichen planopilaris complicate treatment.
community pyrilutamide solution progress log
A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.
community Koshine 826 (Pyrilutamide). Any results after 5 months since it's been released?
Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.
community How far along is Kintor in its Phase II U.S. trials for pyrilutamide?
Kintor's Phase II U.S. trials for pyrilutamide and the process of pharmaceutical drugs coming to market, with a reply from someone who has just ordered 500mg of Pyrilutamide to start their own phase trials.
community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)
A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.
community Feel like im not making process. Had insane shed. (Min/Fin/HRT)
The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.
community 3/9/26 to 7/5/26 results - Oral Min + Fin + GHK-Cu (SubQ)
community Switched to DUT from Fin after 30 months of no progress
community Oral fin 1mg, oral min 2.5 mg - 18 months
community HMI 115 hasn't done phase one yet for AGA?
User asks if HMI 115 hasn't done phase 1 for AGA in humans. Conversation includes treatments Min, Fin, and RU.
community My two months experience with RU58841
community No sides with Ru58841 mixed with stemoxydine, yet sides mixed with fluridil
User mixed RU58841 with stemoxydine, experienced no side effects. Mixing RU58841 with fluridil caused chest tightness.
community A warning to those thinking about using Dutasteride
The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.