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      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Do natural remedies actually work or it is nonsense?

      in Chat  3 upvotes 3 months ago
      Natural remedies may improve hair and scalp health but do not stop hair loss related to DHT or other imbalances. Proven treatments like Minoxidil and Finasteride are recommended for effective results.

      community Doctor rates celebrity hair transplants

      in Transplants  664 upvotes 3 months ago
      Celebrities often use hairpieces, transplants, or medications like Minoxidil to maintain their hairlines. Hair transplants require ongoing medication, and opinions on their success vary.

      community One Year of Progress - 4/1/25 to 3/18/26

      in Progress Pictures  327 upvotes 3 months ago
      A 30-year-old shared their one-year hair regrowth progress using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, Nizoral shampoo, and bi-weekly microneedling. Users discussed the effectiveness of these treatments, with some noting shedding as a temporary phase before stronger regrowth.

      community Insane hairline regrowth with natural supps and minox

      in Update  103 upvotes 3 months ago
      A 23-year-old achieved significant hairline regrowth using minoxidil, saw palmetto, collagen peptides, biotin, omega-3, iron, ketoconazole shampoo, and scalp care techniques, without finasteride or dutasteride. The user attributes success to this combination but is unsure which element is most effective.

      community 42 years old / 6 months / dut, minox, keto, dermaroller

      in Progress Pictures  44 upvotes 4 months ago
      A 42-year-old is using dutasteride, oral and topical minoxidil, ketoconazole, and a dermaroller for hair loss, with noticeable progress after six months. They are questioning if further gains are possible and considering stopping the dermaroller, as advised that future improvements may only involve hair thickening.

      community Starting minoxidil and looking for a few tips

      in Minoxidil  7 upvotes 6 months ago
      The conversation is about using minoxidil for diffuse thinning after finasteride showed no regrowth. Tips include applying minoxidil directly to the scalp, considering potential shedding, and being cautious with combining tretinoin due to possible irritation.

      community My almost 9 year journey with finasteride and minoxidil

      in Progress Pictures  273 upvotes 8 months ago
      A user shared their 9-year experience with finasteride and 3 years with oral minoxidil, noting positive hair maintenance and regrowth without significant side effects. They are considering a hair transplant but are generally satisfied with their current hair condition.

      community 5 months on dut/fin/min progress

      in Progress Pictures  175 upvotes 9 months ago
      The user experienced significant hair regrowth after 5 months using finasteride, dutasteride, and oral minoxidil, despite initial side effects like erectile dysfunction, which resolved after switching from finasteride to dutasteride. The user reports full recovery of hair density and improved skin condition, though the right temple remains slightly recessed.

      community 1 year and 10 Months, 30M, only Fin.

      in Progress Pictures  420 upvotes 9 months ago
      A 30-year-old man experienced significant hair regrowth using only oral finasteride over 1 year and 10 months, with no side effects except increased libido. He started seeing results around the 3-4 month mark and takes finasteride every 2-3 days now, believing he may lose hair if he stops.

      community Should I risk changing to Dutasteride?

      in Finasteride/Dutasteride  10 upvotes 9 months ago
      The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  460 upvotes 9 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Does ketoconazole reduce systemic DHT by much?

      in Treatment  6 upvotes 1 year ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

      community 1.5 years on dutasteride and on and off microneedling

      in Is this regrowth?  60 upvotes 1 year ago
      The user experienced hair regrowth using dutasteride daily, microneedling weekly, and Nizoral shampoo, after stopping minoxidil due to side effects. They also use a mix of pumpkin seed, rosemary, and peppermint oil, and are considering RU58841 for more temple area thickness.

      community 1 years progress. Thoughts please?

      in Is this regrowth?  59 upvotes 1 year ago
      The user is using topical minoxidil and oral finasteride for hair regrowth, with plans for a future hair transplant. They are considering additional treatments like dermastamping and exploring options for dutasteride, which is unavailable in their country.

      community 38M, Topical Min 5% + Infrared Therapy (4 Months In)

      in Progress Pictures  485 upvotes 1 year ago
      A 38-year-old man reports positive results using topical Minoxidil 5% and infrared therapy for hair regrowth over four months, along with Saw Palmetto and Pumpkin Seed Oil supplements. Others suggest adding Finasteride for better maintenance and discuss the role of DHT blockers.

      community Fin + Oral Min 6 months progress (2 pics with dermmatch+toppik)

      in Progress Pictures  607 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the use of finasteride (Fin) and oral minoxidil (Oral Min), with progress shown using hair fibers like DermMatch and Toppik. The original poster plans a hair transplant and mentions side effects like reduced libido from finasteride.

      community Pyrilutamide for non-5AR users?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

      community almost 6 months of progress :)

      in Progress Pictures  535 upvotes 1 year ago
      The user shared their 6-month hair regrowth progress using finasteride, minoxidil, biotin, and iron supplements, along with occasional microneedling and specific shampoos. They reported minimal side effects and no retrograde alopecia, attributing their success to a combination of treatments.

      community Minoxidil should not be underestimated

      in Minoxidil  199 upvotes 1 year ago
      Minoxidil can help with hair regrowth, especially when combined with finasteride, but it doesn't address the root cause of androgenic alopecia. Finasteride is often recommended as the primary treatment, with minoxidil as a supportive option.

      community 3-month progress with fin and min

      in Update  756 upvotes 1 year ago
      A 29-year-old male is experiencing positive hair regrowth after 3 months using oral finasteride (1mg) and topical minoxidil (1ml twice daily), despite side effects like scalp itchiness and dandruff. He plans to continue the treatment long-term and may switch to foam minoxidil to alleviate scalp issues.