The conversation is about using natural DHT blockers like saw palmetto, pumpkin seed oil, and stinging nettle extract for hair loss. Saw palmetto is noted to potentially halt mild hair loss.
The user is using oral minoxidil, ghk-cu, and HGH for hair regrowth, noticing small vellus hairs on the crown. They avoid traditional DHT blockers like finasteride due to side effects, despite skepticism from others about the effectiveness of ghk-cu.
The user is experiencing positive results in hair regrowth using a protocol that includes minoxidil, dutasteride, essential growth serum, argan oil, trioxidil shampoo, ketoconazole shampoo, and microneedling. They express hope and satisfaction with the progress after six weeks of treatment.
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.
A 28-year-old male shares his 12-step hair regrowth routine, including finasteride, minoxidil, RU58841, LLLT, dermarolling, various shampoos, supplements, and a healthy diet. He seeks advice on microneedling frequency and mentions experiencing lowered libido and occasional scalp inflammation.
Hypoxia may enhance hairgrowth by stimulating stem cells, but it could also risk fibrosis. Some users humorously discuss extreme methods like choking while using minoxidil, highlighting the need for new treatments.
User experienced hairgrowth with finasteride and minoxidil, but after using tretinoin, faced aggressive thinning and hair loss. They plan to stop tretinoin for two months to see if the problem improves.
A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.
Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.
The post discusses a hair loss treatment regimen using saw palmetto, pumpkin seed oil extract, EGCG (green tea) extract, grape seed oil extract, rosemary oil extract, and Zix. The user plans to use these DHT-blockers and 5AR inhibitors for six months and report the results.
Upcoming hair loss treatments for those who can't tolerate DHT blockers, focusing on Minoxidil, microneedling, and ketoconazole. Promising treatments include GT20029, PP405, KX-826, and RU58841, though RU58841 may not be safe.
The user has been using finasteride, ketoconazole shampoo, oral minoxidil, and minoxidil foam for hair loss but feels their hair is not as thick as desired. They have stopped using RU58841 due to lack of results and are concerned about hair miniaturization despite these treatments.
Scalp tension may contribute to hair loss by increasing DHT levels, with potential solutions like scalp massages and Botox. Concerns about finasteride's side effects were discussed, and some users shared personal experiences with alternative treatments like scalp massaging and Botox.
Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.
Homelessness is humorously proposed as a solution to hair loss due to less grooming and stress. Treatments like Minoxidil and Finasteride are discussed, with genetics and lifestyle also considered important factors.
A 30-year-old male experienced rapid hair shedding over 6-7 months due to stress, depression, and nicotine/alcohol use, but has since stopped these habits. He seeks advice on remedies, medications, or diet changes to address hair loss.
The conversation discusses the impact of vitamins, stress reduction, and appropriate shampoo on hair health, with the original poster noting slight improvements after two months of using vitamins B5, B6, zinc, and a suitable shampoo. Many users express skepticism about the effectiveness of vitamins for hair loss unless there is a deficiency, emphasizing the importance of addressing DHT and considering 5AR inhibitors.
The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.
Ashwagandha may help with hair loss by regulating thyroid function and reducing stress, but its effectiveness compared to finasteride or minoxidil is debated. Some users report positive effects on hair health, while others are skeptical of its benefits.
Creatine may affect hair loss by reducing PGE2 levels, which could influence hairgrowth. The discussion highlights the need for more research on this potential mechanism.
Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.
The user has tried various treatments for hair loss, including finasteride, dutasteride, RU58841, Pyrilutamide, and several topical growth factors, but continues to experience a receding hairline and thinning. Despite maintaining a healthy lifestyle, the user is unsure why these treatments are ineffective and seeks advice on the underlying cause.
A 25-year-old experiencing genetic hair loss used minoxidil, biotin, and cystine but stopped due to routine fatigue, leading to worsened hair loss and unwanted body hairgrowth. They are hesitant about finasteride due to potential side effects and are seeking advice on effective treatments.
A 21-year-old is concerned about androgenic alopecia and has been using minoxidil for a year, noticing some stabilization in the hairline but fears using it on the whole scalp due to seborrheic dermatitis. Another person suggests considering a psychiatrist for stress management, using Nizoral shampoo, and possibly trying a small dose of finasteride.
Hair loss is worsening despite using finasteride, oral minoxidil, and rosemary oil, possibly due to stress, hormone changes, and environmental factors. Improvement was noted with a soft water filter, but recent stress may have exacerbated the issue.
PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.