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      community Weird scalp problems at 22, early signs?

       2 upvotes 11 years ago
      The conversation discusses scalp issues and hair loss, with treatments like Accutane, Nizoral, and H&S being used. Suggestions include considering finasteride, minoxidil, and jojoba oil, with caution advised for the latter.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  260 upvotes 1 year ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle

      in Chat  1 upvotes 11 months ago
      The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  13 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.