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      community 6 months of hair loss. 0.5mg dutasteride daily, minoxidil topically nightly, nizoral shampoo a few times, vitamin D has been optimized for several weeks, now starting Zinc supplementation

      in Update  13 upvotes 1 year ago
      A 27-year-old male experiencing increased hair loss despite using 0.5mg dutasteride daily, minoxidil nightly, and optimizing vitamin D, is considering zinc supplementation and seeking a dermatology referral. Concerns about potential shedding, thyroid levels, and zinc dosage are discussed, with advice to monitor and avoid over-supplementation.

      community Increasing DHT level after 5 months of Finasteride

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      OP noticed an increase in DHT levels after 5 months of using finasteride and is unsure if the drug is effective or if other factors like stress or vitamins are influencing the results. Users suggest testing the medication for authenticity, consulting a doctor, and possibly trying a different brand or dosage.

      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 9 months ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community 22M High Estrogen after blood test

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      A 22-year-old male with high estrogen levels is considering finasteride for hair loss but is concerned about potential side effects due to his hormone levels and family history of diabetes. Users suggest consulting a doctor, possibly an endocrinologist, and considering lifestyle changes like diet and exercise to address visceral fat and insulin resistance before starting treatment.

      community Getting bloods done whilst on finasteride

      in General  98 upvotes 1 year ago
      Finasteride can affect hormone levels within two weeks, and a break of several weeks is recommended for baseline results. Monitoring E2 and testosterone is suggested to assess the risk of gynecomastia.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 4 weeks ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community Low-Dose Oral Minoxidil Does Not Significantly Affect BP

      in Minoxidil  178 upvotes 1 year ago
      Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.

      community Where the fuck are the pyrilutamide GB guys?

      in Chat  23 upvotes 4 years ago
      The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

      community Insulins impact on androgen levels

      in Research/Science  16 upvotes 4 years ago
      Controlling insulin levels through intermittent fasting and a low glycemic diet may improve hair quality by reducing androgens. It's important to maintain proper nutrition, including electrolytes and protein, during fasting.

      community i need your advice please tell

      in Product  2 upvotes 2 years ago
      The user is experiencing stage 2 hair loss and thinning, noticing more scalp visibility with short hair. They are considering diet, yoga, scalp massage, supplements, and a serum recommended by their doctor, and questioning if it's safe to stop using the serum and whether to get a blood test since hair loss isn't a family trait.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 4 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community My Near-Nuclear Stack is Saving me; Hyperresponder?

      in Progress Pictures 1 year ago
      An 18-year-old is using a high-dose hair loss treatment regimen including finasteride, minoxidil, dutasteride, and plans to add RU58841 and bimatoprost, despite warnings from others about the risks. The user is determined to reverse hair loss but acknowledges the potential dangers and does not recommend others follow their approach.

      community What vitamin D level would cause hair loss?

      in Female  13 upvotes 4 years ago
      A user experiencing excessive hair shedding and a receding hairline is questioning if low vitamin D levels could be the cause, despite levels being within the normal range. Replies suggest that while vitamin D deficiency can cause hair loss, it might not be the issue in this case.

      community Got the bloodwork results and it’s interesting

      in Treatment  15 upvotes 1 month ago
      The user has high DHT levels despite using dutasteride, which may not be effective due to potential damage or spoilage. They are considering a hair transplant if DHT levels don't decrease after two years.

      community Can HMI-115 reverse miniaturization?

      in Research/Science  12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 8 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community Switching between topical(10%) and oral(2.5mg)

      in Minoxidil  3 upvotes 11 months ago
      The user is considering switching between topical minoxidil (10%) and oral minoxidil (2.5mg) to manage hair shedding around the temples, while also using a dermaroller and biotin. They are concerned about the potential side effects of oral minoxidil, such as hypertrichosis, and the impact on hair shedding if they stop using it.
      One-sided diffuse thinning - what should I do?

      community One-sided diffuse thinning - what should I do?

      in General  101 upvotes 6 months ago
      The user is experiencing one-sided diffuse thinning and has been using finasteride and liquid minoxidil for 4-5 years with minimal results. They are considering whether to save for a hair transplant or address scalp sensitivity and irritation first.

      community How's your progress on kx-826 (pyrilutamide)?

      in Treatment  11 upvotes 1 month ago
      People are discussing their experiences with kx-826 (pyrilutamide) for hair loss, using concentrations of 0.5% and 0.9%. They are sharing personal results and progress with this treatment.

      community questions for the pyrilutamide users here

      in Treatment  7 upvotes 3 years ago
      The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.

      community Sweet Lord my DHT itch is finally gone

      in Chat  49 upvotes 3 years ago
      Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

      community SHEDDING doesn't mean shit. Stop worrying about it!!

      in Chat  91 upvotes 5 years ago
      Hair loss sufferers becoming hyper aware of shedding, and the various treatments available for reducing shedding. The conversation also discussed differentiating between shedding and balding, as well as the potential side effects from using certain treatments.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.