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720-750 / 1000+ resultscommunity What’s the consensus on RU58841 vs Pyrilutamide (Kx-826)?
RU58841 and Pyrilutamide (Kx-826) are both topical anti-androgens, but neither is effective for hair regrowth. RU58841 has more anecdotal support, while Pyrilutamide has progressed further in trials, though both have limitations.
community Update from December's Pyrilutamide GB?
community Found an interesting little article
A new painless microneedle patch shows promise in reversing hair loss. The discussion focuses on potential new treatments beyond common options like Minoxidil, finasteride, and RU58841.
community progress pics (HRT, fin, min, microneedling) (35, trans non-binary)
A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.
community Xeljanz medication for alopecia universalis?
community Almost 3 months | Topical Min (5%), 1 mg Fin, Microneedling, Biotin + Vitamin D Supplement
The conversation discusses a successful hair regrowth treatment involving topical Minoxidil (5%), 1 mg Finasteride, Microneedling, and Biotin + Vitamin D supplements. The user shares their routine and receives positive feedback on the significant progress made in just three months.
community Has anyone used the new liposomal topical fin from Hasson and Wong?
The conversation discusses a new liposomal topical finasteride from Hasson and Wong, available in Canada and Italy, soon in the US, costing $40/month. It claims to reduce scalp DHT by 50% without affecting serum DHT, potentially benefiting those who can't tolerate oral finasteride or RU58841.
community What's more reliable right now, pyrilutamide or RU?
Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.
community Regimen update - Added oral Minox and RU
The user updated their hair loss treatment to include daily dutasteride, oral minoxidil, topical dutasteride with minoxidil and tretinoin, and RU58841. Commenters feel the extensive treatment is unnecessary for the user's level of hair loss.
community Is diffuse thinning wise to do HT?
community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data
ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.
community RU58841 longterm use and expectations.
community 5 months update: 5mg dut, 5mg biotin, trop min 5% 2x day, dermaroll 1-2x week
OP is using 0.5mg dutasteride, 5mg biotin, 5% topical minoxidil twice daily, and dermarolling 1-2 times a week for hair loss. OP reports no side effects and is happy with the progress after 5 months.
community making a clascoterone lotion from powder
A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.
community Anyone tried Dr. Rassman's topical Finasteride? Is it liposomal?
The conversation discusses concerns about Dr. Rassman's topical Finasteride, specifically whether it is liposomal or glycol-based. Dr. Rassman insists on providing the correct liposomal formulation and urges patients to contact him if they receive the wrong product.
community Big 3 + dermaroller update
A user's experience with the Big 3 (minoxidil, finasteride and RU58841) hair loss treatment along with dermarolling. The dermaroller pin was 1.5mm used once per week and drew some blood but not a lot.
community AH-001 another topical AR degrader beside GT20029, completed Phase I
AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.
community How should I switch from topical to oral min ?
Switching from topical to oral minoxidil for hair loss treatment. The user seeks advice on dosage and whether to overlap or combine both forms for better results.
community Switching from oral minoxidil to topical minoxidil after 20 months due to health issues. Any advice? Never used topical before. Do I have to use Tretinoin?
Switching from oral to topical minoxidil due to health issues, with advice on using tretinoin to enhance effectiveness. Tretinoin can improve minoxidil absorption and effectiveness, potentially reducing application frequency.
community Is this the nuclear stack? Wanna go from NW3 to NW1 at the age of 23
A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.
community Pyrilutamide (KX-826) personal consideration
Pyrilutamide (KX-826) is discussed as an anti-androgen treatment for hair loss, with mixed user experiences. Some users report no results, while others find it mildly effective.
community Where do you get your RU58841? Do you do use powder or solution?
RU58841 for hair loss, discussing sources, application methods, and carriers like PG + ethanol or liquid minoxidil. Users share experiences with premixed solutions and powder forms, noting price differences and storage importance.
community Show of hands (US people), who's ordering pyrilutamide?
People are discussing ordering pyrilutamide for hair loss treatment in the US. The treatment is from Kintor's subsidiary company and is available on Amazon.
community Male, NW2, One Month on Fin, Considering Oral Min Due to Cost and Convenience
The user is considering switching from topical Minoxidil to oral Minoxidil due to concerns about maintaining a topical routine. They have already started finasteride and are trying to prevent further hair loss progression.
community Ru58841 and pyrilutamid receptor binding affinity vs spironolactone?
Female considering adding topical anti-androgen, seeks advice on RU58841 or pyrilutamid's binding affinity compared to spironolactone.
community Advanced AGA and DUPA at 25. Starting Nuclear Stack: Day 1
User starts Nuclear Stack treatment for hair loss, including Dutasteride, Minoxidil, RU58841, Derminator 2, and supplements. Seeks advice on storing and dosing RU58841.
community [M30] 15 months progress on Oral Dutasteride and Sublingual Minoxidil
User shared 15-month progress using Oral Dutasteride and Sublingual Minoxidil for hair loss. Treatment improved hair density, now considering hair transplant with fewer grafts.
community I take Ulo topical finasteride 0.005%, topical minoxidil, oral minoxidil 5 mg, a liquid multivitamin, collagen powder, and liquid biotin. I also microneedle with a Dr. Pen and use red light therapy.
A 21-year-old is using a combination of topical finasteride, topical and oral minoxidil, a liquid multivitamin, collagen powder, liquid biotin, microneedling, and red light therapy to address hair thinning. They are cautious about side effects and unsure if their hair loss is due to DHT or past brushing habits.
community Dutasteride Mesotherapy in USA?
User is seeking information on obtaining dutasteride vials for mesotherapy in the US, mentioning a closed source and lack of local clinic options.