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      community 4 month minoxidil foam + 1MM dermarolling update.

      in Progress Pictures  526 upvotes 5 years ago
      User sshamu's progress pictures of 4 months using minoxidil foam and 1MM dermarolling for hair loss, which resulted in impressive results. There is also discussion about how often to use the treatments, as well as potential side effects of finasteride.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 2 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community COQ10 + PQQ for scalp inflammation??

      in Chat  6 upvotes 1 year ago
      A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.

      community About Pyrilutamide Phase II US Trial

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  112 upvotes 10 months ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community LPT: Sebhorric Detmatitis Treatment

      in Treatment  6 upvotes 8 years ago
      Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.

      community NW7 recovery attempt, a little over 2 month progress. 1.25mg fin, 5mg topical minox twice a day. Pyrilutamide for 1 month, switched to RU58 2 weeks ago, weekly microneedling 1.5mm

      in Treatment  9 upvotes 3 years ago
      A user is attempting to recover from severe hair loss using 1.25mg finasteride, 5mg topical minoxidil twice daily, pyrilutamide for a month, RU58841 for two weeks, and weekly microneedling at 1.5mm. They have seen new hair growth after two months and plan to continue the treatment for a year with the hope of regrowing enough hair for a transplant.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 5 month progress on Min, Fin, and dermastamping

      in Progress Pictures  4 upvotes 1 week ago
      The user shared their 5-month progress using Minoxidil, finasteride, and weekly dermastamping, noting improvements in their hairline and crown. They also use a saw palmetto shampoo and have not experienced shedding yet.

      community 13 WEEKS MICRONEEDLING MONOTHERAPY

      in Microneedling  187 upvotes 3 years ago
      A user's experience with microneedling monotherapy and potential treatments such as finasteride, minoxidil, Stemoxydine, rosemary oil, peppermint oil, and RU58841 for reversing hair loss.

      community Almost 3 months on pyrilutamide

      in Treatment  32 upvotes 3 years ago
      A user's experience with Pyrilutamide, which they have been taking for 3 months to treat their aggressive male pattern baldness. The user reported that the medication decreased shedding and was hopeful it would work as advertised.

      community How to get rid of dandruff once and for all?

      in Treatment  7 upvotes 3 years ago
      A 20-year-old male using Minoxidil and finasteride for 6 months and keto shampoo for 5 months saw initial improvement in dandruff, but the condition returned. He recently started using 3% salicylic acid shampoo and seeks advice for persistent dandruff, which is oily and localized to the left side of his scalp.

      community Oils, Saw Palmetto, Microneedling every 3 days, DHT Shampoo

      in Progress Pictures  300 upvotes 1 year ago
      The user experienced positive hair regrowth using a routine of microneedling every 3 days, applying a blend of castor oil with peppermint and rosemary, bhringraj oil, and moringa oil, and using Pura D'Or DHT-blocking shampoo. They also take multivitamins and saw palmetto daily, reporting no side effects from saw palmetto.

      community Finally about to start Pyriltamide (ONLY Pyriltamide)

      in Chat  63 upvotes 1 year ago
      A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

      community Depressed that topical dut+min is causing unwanted hair everywhere on my face. Is there anything can I do?

      in Minoxidil  21 upvotes 2 years ago
      The conversation is about a user experiencing excessive hair growth on their body due to using topical minoxidil and dutasteride. The suggested solutions are shaving off the excess hair or considering laser epilation. It is mentioned that dutasteride does not cause extra hair growth, while minoxidil can stimulate hair growth in unintended areas. The user is advised to lower the dosage, concentration, or frequency of use and only apply the treatment to the desired areas.

      community Dutasteride and minoxidil : 5 months

      in Is this regrowth?  88 upvotes 4 months ago
      The user is using dutasteride and minoxidil foam for hair regrowth, applying minoxidil once daily due to side effects from the liquid form. They plan to increase dutasteride dosage and possibly apply minoxidil twice daily, while also using ciclopirox olamine shampoo and sulfur soap.

      community Dermal incision with verteporfin

      in Research/Science  4 upvotes 4 months ago
      Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community How do you prevent infection with derma needling / derma stamping?

      in Microneedling  1 upvotes 10 months ago
      The conversation discusses preventing infection from derma stamping for hair loss treatment, with suggestions to reduce needle depth and consider alternatives like tretinoin. The user experienced irritation possibly from zinc chloride and stopped using the shampoo and derma stamping.