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      community Pyrilutamide - cosmetic vs. clinical trials

      in Treatment  3 upvotes 3 months ago
      The conversation discusses the difference between the commercially available Pyrilutamide and the version in clinical trials. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

      in Chat  6 upvotes 6 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 3 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community Shampoo without salicylic acid

      in Product  2 upvotes 8 months ago
      A user is seeking a hair-loss shampoo without salicylic acid due to an allergy. Recommendations include using Finasteride, Minoxidil, and Nizoral Anti-Dandruff Shampoo (ketoconazole), while avoiding Nizoral Scalp Psoriasis Shampoo & Conditioner.

      community Any topical I can add midday to boost results?

      in Treatment  3 upvotes 4 months ago
      The user is using Minoxidil 5% foam in the morning and a Minoxidil 5% + Finasteride 1% solution in the evening for hair loss. They are seeking advice on additional topical treatments to use midday, such as caffeine serums, peptides, Redensyl, or natural anti-inflammatories.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  408 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Best source for RU58841 in Australia?

      in Treatment  3 upvotes 3 months ago
      The conversation discusses finding a source for RU58841 in Australia. Users suggest that while RU58841 is effective, it may harm the scalp, and recommend trying koshine's kx as a safer alternative.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 9 months ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community Red and ichy pimples/rash from applying topical minoxidil

      in Chat  2 upvotes 2 months ago
      The user experienced red pimples and a rash from using topical minoxidil, possibly due to propylene glycol. Suggestions included seeing a dermatologist, switching to foam without propylene glycol, using Nizoral, and adjusting application timing.

      community I Get Side-Effects from Anti-Androgens

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

      community Using Topical Minoxidil And Pyrilutamide Together

      in Treatment  1 upvotes 1 year ago
      Mixing 1ml of topical Minoxidil and Pyrilutamide (2ml total) together in a container and applying immediately is being discussed. The concern is whether this method degrades or compromises the efficacy of either compound.

      community AGA responded to steroid shots? Biopsy wrong? Please help!

      in Female  2 upvotes 1 year ago
      A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

      community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community 3 months on hims fin/min topical spray

      in Progress Pictures  331 upvotes 2 years ago
      The conversation discusses a user's positive experience with a hair loss treatment using a topical spray containing finasteride and minoxidil. Some users express interest or skepticism, while the original poster also mentions using biotin gummies, fish oil, and a multivitamin.

      community I am doing an experience with RU58841

      in Treatment 6 months ago
      The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 1 year ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Lab results from actifolic RU58841

      in Product  39 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

      community Wednesday after micro needling through Friday today.

      in Treatment  1 upvotes 1 year ago
      The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.