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      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  195 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW

      in Minoxidil  7 upvotes 2 years ago
      A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 3 years ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community DS Labs SOD suppliments, anyone try them?

      in Product  4 upvotes 1 year ago
      The conversation is about trying DS Labs SOD supplements for hair loss, which contain ingredients like Genistein, B-sitosterol, and Biotin. The user is considering adding these supplements to their existing hair care routine.

      community What’s the update on Pyrilutamide?

      in Chat  12 upvotes 3 years ago
      Pyrilutamide is seen as a last hope for those who can't take finasteride, with promising results reported. However, there's uncertainty about the quality and consistency of Pyrilutamide from black market sources.

      community Any clinical study on cysteine alone for hair loss?

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 2 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Anyone only on RU or Pyrilutamide?

      in Research/Science 1 year ago
      The conversation discusses using RU58841 or Pyrilutamide for hair loss, with some users suggesting switching to more proven treatments like oral or topical finasteride. One user reports no progress with RU58841, finasteride, and minoxidil, and mentions experiencing regression.

      community Good lord! Serioxyl stemoxydine smells TERRIBLE

      in Product  14 upvotes 2 years ago
      The conversation is about a user complaining about the strong smell of a stemoxydine serum used for hair loss. Other users suggest that the product might be counterfeit due to its unpleasant odor.

      community Broccoli supplement (Sulforaphane) for better Minox results?

      in Minoxidil  4 upvotes 3 years ago
      Broccoli or sulforaphane supplements are unlikely to improve Minoxidil results due to the need for an unrealistically large dose. Tretinoin, micro-needling, and low-dose oral Minoxidil may be more effective for those lacking the necessary enzyme in the scalp.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 3 weeks ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community Does Pyrilutamide lowers sebum production?

      in Treatment  2 upvotes 6 months ago
      Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

      in Chat  5 upvotes 7 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community 4 Month Update on Pyrilutamide

      in Update  11 upvotes 3 years ago
      Hair loss treatment with Pyrilutamide, Minoxidil, and Finasteride showed improvement after 4 months. Shedding reduced, hair feels stronger and healthier, with no side effects.

      community Pyrilutamide 0.5 or 0.025% topical fin for maintaining?

      in Basic Questions  91 upvotes 1 month ago
      The user is considering switching from pyrilutamide to 0.025% topical finasteride due to concerns about effectiveness and past side effects from a scalp elixir. They aim to maintain hair until new treatments like breezula or GT00029 become available.

      community What's your thoughts on Pyrilutamide

      in Product  5 upvotes 5 months ago
      The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.

      community Is pyri and gt20029 worth the hype????

      in Update  6 upvotes 2 years ago
      The conversation discusses the effectiveness of pyrithione zinc and GT20029 for hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 4 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community Mixing Stemoxydine 5% with premixed solution of RU58841 5%

      in Research/Science  2 upvotes 2 years ago
      The user is using Dutasteride, Nizoral, and RU58841 for hair loss and is considering mixing RU58841 with Stemoxydine for better scalp coverage but is concerned about the potential degradation of RU58841 when mixed with a water-based solution. They are seeking advice on the feasibility of this mixture.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 1 year ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.