Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
The user successfully overcame finasteride side effects by lowering the dosage and adding zinc and vitamin B6 supplements. They also micro-dosed dutasteride and resumed weight lifting.
The user experienced significant hair regrowth using a daily capsule containing 1mg finasteride, 2.5mg minoxidil, and 10mg biotin, with noticeable results after 3-4 months. They reported a decrease in libido as a side effect and considered switching to minoxidil only, but were advised against it.
The conversation discusses using both oral and topical forms of finasteride and minoxidil for hair loss. Concerns about potential overkill and side effects are raised, but no side effects are reported from using oral finasteride and topical minoxidil.
A user reports significantly reduced hair shedding by using a topical mixture containing 10% Minoxidil, 0.1% Melatonin, 5% Azelaic Acid, 5% Rosemary Oil, and 5% Peppermint Oil, and attributes the success mainly to Melatonin. They also use a copper peptide serum (AHK-Cu) for hair growth and Ketoconazole shampoo for scalp cleaning, but have stopped using other treatments like Finasteride and RU58841.
A user shared their experience with hair loss and recommended supplements like magnesium, vitamin D, vitamin C, zinc, iron, and protein, along with using a dermaroller. They noted benefits such as accelerated fat loss, muscle growth, better digestion, increased testosterone, and improved hair and skin quality.
Finasteride improved hair thickness for someone with diffused thinning after 11 months, with no side effects. Patience and consulting a dermatologist are advised, and minoxidil is suggested for additional support.
The user shared an 11-month hair loss treatment update, maintaining the same regimen but adding vitamins and increasing minoxidil application to 1ml during the day. It's unclear if the vitamins contributed to any changes.
The conversation discusses using topical dutasteride as an alternative to oral finasteride to prevent hair shedding caused by creatine supplementation. Users share experiences with finasteride, dutasteride, and creatine, noting potential side effects and effectiveness concerns with topical treatments.
A sugar gel called 2-deoxy-D-ribose (2dDR) shows potential for promoting hair regrowth by increasing blood supply to hair follicles, similar to Minoxidil, but its effectiveness in humans is unproven. It may benefit those who don't tolerate Minoxidil, but it is not a replacement for treatments like Finasteride or RU58841.
User "logart89" claims DUT 3 times a week is better than daily FIN for hair loss. Their routine includes DUT, topical DUT, stemoxydine and alfatradiol mix, 5% minoxidil with tretinoin, and weekly derma stamping.
The user experienced unexpected hair volume increase after combining scalp massages with topical minoxidil and oral finasteride. They plan to continue this regimen, noting a reduction in hair shedding.
The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
Mixing topical finasteride with essengen f and stemoxydine creates 0.25mg dose in 2ml. Minoxidil max suggests mixing 8.5ml essengen f with 60ml solvent for 0.25mg dose in 1ml.
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.
The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.
Despite using finasteride and dutasteride for years, the user experienced continued hair thinning and is now visibly balding. They are considering trying minoxidil but are doubtful about its effectiveness.
A man shared his 6.5-month progress using finasteride, a derma roller, and biotin supplements for hair loss, with no side effects and overcoming two shedding phases. Commenters are impressed, noting hairline improvement and discussing the potential of these treatments in regrowing hair, especially at the temples.
The user is taking oral minoxidil, dutasteride, and finasteride but hasn't seen improvement in hair thickness. They experienced hair loss after switching from topical to oral minoxidil.
Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.
The user is using a combination of topical and oral treatments containing Finasteride and Minoxidil, along with supplements like Biotin, Saw Palmetto, and vitamins, to combat hair loss. They are also incorporating lifestyle changes such as a whole foods diet, exercise, and improved sleep to support their regimen.
The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.
The conversation is about whether stemoxydine can shorten the dormant phase after a hair transplant, known as the ugly duckling phase. There is skepticism about whether it actually works as claimed.
The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.
The user experienced serious hair loss and started using finasteride, minoxidil, microneedling, and argan/rosemary oil. They are asking if they can maintain hair regrowth by stopping minoxidil and continuing only with finasteride and microneedling.