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community Hot Take: Betting on PP405 can backfire

in Research/Science 81 upvotes 1 year ago

PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

in Chat 18 upvotes 4 years ago

People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

community I'll defeat the norwood reaper with kitchen sink light

in Treatment 27 upvotes 4 years ago

A user who is using a combination of oral and topical treatments, including finasteride, minoxidil, pyrilutamide, dutasteride, microneedling, and ketoconazole shampoo in order to combat hair loss. Another user gave the original poster a word of warning about overusing the ketoconazole shampoo.

community 1 year Post HT 2200 Grafts + fin 8 Months Then switched to dut

in Progress Pictures 519 upvotes 4 years ago

A user who experienced positive results from using finasteride and dutasteride to treat their hair loss, with 2000 grafts being transplanted in the temples area for further improvement. They also discussed cost and other treatments such as minoxidil.

community Why Is No One Talking About Chromosome 20?

in Chat 32 upvotes 10 months ago

Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

community Post TCA pic and two month in, just posting baseline and an update.

in Progress Pictures 5 upvotes 5 months ago

The conversation is about a user's hair loss treatment regimen, which includes Dutasteride, oral Minoxidil, topical Dutasteride, Minoxidil sulfate, antioxidants, and various supplements. The user is also using a derma stamp and has paused Tretinoin due to a TCA peel recovery.

community Can anyone advise me on the best brand of 2% Minox to use and mix with pyrilutamide powder

in Treatment 1 upvotes 3 years ago

Best 2% Minox brand for mixing with pyrilutamide powder and retinoic acid sought. Advice on specific treatments discussed.

community are all vellus hairs likely to go terminal if fin/dut + min + tret are used long enough?

in Treatment 6 upvotes 4 years ago

The user has been using a combination of finasteride/dutasteride, minoxidil, tretinoin, and hydrocortisone with microneedling and ketoconazole shampoo for hair loss. They are asking if the baby hairs growing will turn into terminal hairs with continued treatment.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 450 upvotes 3 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community Binding affinity of pyrilutamide!

in Update 172 upvotes 4 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

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