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120-150 / 1000+ resultscommunity (/r/science X-post): Stress may turn your hair grey. The appearance of grey hairs after periods of stress or skin damage could be the result of depletion of stem cells from the base of the hair follicle, according to a new study : science
community Fin ED is primarily blood flow related, not hormonal as such - a theory
The conversation discusses the theory that finasteride-induced erectile dysfunction (ED) is related to blood flow rather than hormonal changes. The user suggests that lowering LDL cholesterol aggressively might improve ED symptoms for those on finasteride.
community Fluridil downregulates androgen receptor expression?
Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.
community (Topical) Quercetin might be a good add on to the hair loss stack
Quercetin might help with hair loss by inhibiting HSP-70, which increases androgen receptors. Concerns include its staining properties and unclear topical absorption.
community After giving hair fibers a try, I can’t stop looking at myself in the mirror
User tried cheap hair fibers from Amazon, significantly improved appearance of thinning hair. Fixing spray recommended to prevent fibers from blowing off.
community How obvious is it that I am using hair fibers to thicken my hairline?
The user uses Toppik hair fibers to thicken their hairline and has switched from finasteride to dutasteride and oral minoxidil, noticing more hair thickening. Most responses indicate the hair fibers are not noticeable, and many suggest the user doesn't need them as their hair looks natural and good for their age.
community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc
Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.
community Well, I guess this puts the scalp tension theory to bed
Hair loss discussion includes various causes like DHT, blood flow, and skin fibrosis. Treatments mentioned are Minoxidil, Finasteride, and RU58841.
community I was addicted to hair fibers for 11 years
A person used hair fibers for 11 years to hide hair loss, which affected their social life. They had a hair transplant, improving their life, and recommend addressing hair loss directly.
community This tells you if you're shedding or losing hair (along with other things like fibrosis)
High frequency ultrasonography and HR-MRI can help identify hair shedding causes like inflammation and fibrosis. The conversation discusses the potential of using these technologies to evaluate treatments like Verteporfin for hair regeneration.
community Topical melatonin shows some promise.
community RU58841 - Side Effects - Day 4: Chest Pain & Tightness, Bloodshot Eyes and some sort of inflammation/irritation on my throat.
RU58841 caused chest tightness, throat irritation, and headaches, leading the user to stop its use. The user plans to restart with a lower dose if symptoms fully disappear but remains cautious due to anxiety and side effects.
community Exploring all options - Scalp tension theory
The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.
community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.
A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.
community Do the more newer gen topical retinoids e.g. tazarotene outperform tretinoin in inducing follicular sulfotransferase activity?
community Fin effects on prostate sensation for MSM
Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.
community Pirfenidone - The answer to fibrosis and baldness
Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.
community [27M] FUE 14 days recovery progress
A user shared their 14-day recovery progress after a 3450 graft FUE hair transplant in Turkey, noting faster healing possibly due to hydrolyzed collagen supplements. They asked if others had similar experiences with or without such supplements.
community Just a heads up guys. The DHT itch.
community Beneficial supplement (my experience)
The user shares their experience with hair loss treatments, specifically finasteride, and discusses the side effects like lowered libido and motivation. They recommend trying tyrosine to counter these effects, noting it improved their libido and energy levels.
community Is diffuse thinning wise to do HT?
community Could PP405 restore extracted hair follicles after transplant?
PP405 cannot restore extracted hair follicles after a transplant as they are removed, not dormant. Combining verteporphin with wounding and PP405 is suggested but not confirmed effective.
community Update on Amplifica (new drugs) and Engraft (new hair transplant technology)
community Preliminary results from verteporfin case study. Looks like donor hairs could be starting to regrow after FUE extraction! This could be huge!
A case study that suggests verteporfin may be able to help regrow donor hairs after FUE extraction, and the potential implications of this result. Treatments discussed include Minoxidil, Finasteride, and RU58841.
community How You Can Help Speed Up the Verteporfin Trials
The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.
community Thoughts on STEM cell hair transplants?
community Me When The Surgeon Starts Injecting Verteporfin Into My Scalp After Committing Genocide On My Donor Area
Exploring the potential of using Verteporfin to grow follicles in combination with microneedling, as well as the cost of administering a single injection and the possibility of combining it with minoxidil.
community Which compounds in Saw Palmetto are actually beneficial?
Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.
community Novel effect of sildenafil (cialis) on hair growth
Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.