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      community My protocol for combatting hair loss

      in Treatment  4 upvotes 4 years ago
      The conversation is about a hair loss treatment protocol involving microneedling, finasteride, RU58841, minoxidil, ketoconazole shampoo, and a scalp massager with oils. Some users advise starting with fewer treatments like finasteride, minoxidil, and microneedling to avoid potential side effects.

      community Pyrilutamide or RU or cb-03-01?

      in Minoxidil  2 upvotes 7 months ago
      The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

      community Dut mesotherapy shed or not working

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced initial success with topical minoxidil and dutasteride mesotherapy but is now losing more hair and unsure if it's due to shedding or ineffective treatment. They are considering whether to try a different approach.

      community Is hair cloning and setipiprant coming in 2020?

      in Question  5 upvotes 9 years ago
      The conversation discusses potential hair loss treatments, including hair cloning, setipiprant, and topical finasteride, questioning their availability and effectiveness as permanent cures. The user is inquiring about the release dates and efficacy of these treatments.

      community Female with hair loss - turns out it’s been thyroid cancer

      in Update  284 upvotes 2 years ago
      A woman with hair loss discovered she has thyroid cancer, which was found during an MRI and confirmed with an ultrasound. She advises others with symptoms to see a doctor and shares that her cancer was detected after her dog sniffed her neck and she experienced neck pain.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 year ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Doubts about my new exosomes treatment

      in Treatment  6 upvotes 11 months ago
      A 22-year-old is frustrated with ongoing hair loss despite using treatments like topical minoxidil, finasteride, microneedling, oral dutasteride, and oral minoxidil. Their dermatologist suggests treating scalp inflammation with oral tretinoin and using exosomes for alopecia.

      community Question on lifestyle changes when on treatment

      in Chat  3 upvotes 2 months ago
      The conversation is about using topical finasteride for hair loss and concerns about its application, side effects, and practicality. Users suggest switching to oral finasteride for convenience, despite potential side effects.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  14 upvotes 2 years ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Finally about to start Pyriltamide (ONLY Pyriltamide)

      in Chat  63 upvotes 1 year ago
      A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

      community Does drinking topical minoxidil increase cancer risk?

      in Minoxidil 10 months ago
      A user has been using sublingual minoxidil for hair loss due to difficulty obtaining pills and is concerned about cancer risk from ethanol exposure. Other users advise against this method, suggesting topical application instead, and debate the potential risks of ingesting topical minoxidil.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

      in Research/Science  57 upvotes 11 months ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community Losing Hope, Not Sure if I should keep fighting

      in Update  5 upvotes 5 years ago
      The user is experiencing severe hair thinning and is using multiple treatments including topical finasteride, minoxidil, tretinoin, latanoprost, oral minoxidil, dutasteride, saw palmetto, and derma wounding. They are considering adding RU58841 and are contemplating a hair transplant and exosomes due to frustration with current results.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community Treatment effectiveness for oral vs topical

      in Treatment  3 upvotes 8 months ago
      Oral treatments for hair loss, like Dutasteride and Minoxidil, may be more effective than topical ones, though topical formulations can be similarly effective except for Minoxidil. Topical treatments can be a chore to apply and are often used as supplements to oral treatments.

      community Shedding and thinning won’t stop on Nuclear protocol

      in Treatment  18 upvotes 2 years ago
      The user is using a combination of hair loss treatments including dutasteride, minoxidil, RU58841, low-level laser therapy, ketokonozole, supplements, Viviscal, Nutrafol, microneedling, PRP, and scalp Botox injections, but is still experiencing hair shedding and thinning. Despite being on this regimen for two years, the user's hair condition is worsening, and they are seeking advice on what else they can do.

      community Topical solution recommendation

      in Treatment  2 upvotes 11 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Opinion on the recent clascoterone breakthrough?

      in Treatment  3 upvotes 5 months ago
      Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.