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      community What's your thoughts on Pyrilutamide

      in Product  6 upvotes 4 months ago
      The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.

      community Topical finasteride results .1%

      in Progress Pictures  15 upvotes 2 years ago
      The user has been using 0.1% topical finasteride and topical minoxidil for hair loss, and has now been prescribed Dutasteride. They also use a derma pen, ketoconazole shampoo, and a mix of oils for treatment.

      community Tretinoin+Minoxidil heavy shedding. (31M)

      in Treatment  10 upvotes 2 years ago
      A person using Minoxidil, Finasteride, Microneedling, and recently added Tretinoin is experiencing heavy shedding and thinning hair. They suspect Tretinoin has made them respond to Minoxidil and are seeking others with similar experiences.

      community 5 months on min and topical fin.

      in Is this regrowth?  37 upvotes 7 months ago
      The user has been using a combination spray of finasteride, minoxidil, and tretinoin for 5 months, along with microneedling and biotin, and is uncertain about hair regrowth progress. Other users suggest more time is needed for results, with peak results at 2 years, and mention oral dutasteride as an effective treatment.

      community Making minoxidil + azelaic acid type recipes?

      in Minoxidil  7 upvotes 6 years ago
      The conversation is about making a hair loss treatment combining minoxidil with azelaic acid, retinol, and caffeine, similar to the product Xandrox. The user has tried Xandrox but switched to Kirkland minoxidil for cost reasons and is seeking advice on creating a similar mixture.

      community M30, month 5 of dutasteride and minoxidil

      in Progress Pictures  250 upvotes 6 months ago
      A 30-year-old male experienced significant hair regrowth after five months of using topical minoxidil (5% foam) and oral dutasteride (0.5 mg daily). The user reported no side effects and was grateful for the progress, despite the rapid gains slowing down.

      community Scalp Biopsy Results - Almost 2 Years Dutasteride, Still Worsening

      in Update  24 upvotes 7 months ago
      Dutasteride and finasteride are not effectively stopping hair loss for some users, despite long-term use. Some are considering or using RU58841, pyrilutamide, and other treatments like microneedling, while also managing seborrheic dermatitis with diet and topical solutions.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 weeks ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community 4.5 months of microneedling – progress

      in Microneedling  300 upvotes 5 years ago
      A user who has had positive results from using a regimen of microneedling, finasteride, minoxidil, peppermint oil, keto shampoo and DHT organic shampoo for hair growth. The conversation also addressed whether to use .5mg or 1mg of finasteride and the difference between dermapens and rollers.

      community topical minoxidil (5%) & kx826 (.5%) update.

      in Progress Pictures 7 months ago
      The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.

      community New Hair Loss Treatment: Adipose Derived Secretomes

      in Research/Science  17 upvotes 11 months ago
      Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

      community 8 Weeks Progress. DUT and topical MIN

      in Progress Pictures  158 upvotes 8 months ago
      The user shared their 8-week hair regrowth progress using 0.5mg dutasteride, twice-daily topical minoxidil, and weekly 1.5mm microneedling. They noted visible improvement, though some users suggested reducing microneedling depth to avoid potential scalp damage.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 2 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community 3 month progress! (Min and derma only)

      in Is this regrowth?  239 upvotes 1 year ago
      The user reported hair regrowth progress using minoxidil and dermapen, considering adding finasteride. Others shared experiences with minoxidil, finasteride, and microneedling, recommending finasteride for long-term results but noting potential side effects.

      community Extremish regimen - dermarolling too hard?

       4 upvotes 8 years ago
      The user is using a hair loss treatment regimen that includes RU58841, minoxidil mixed with finasteride, adenosine, dermarolling with lidocaine cream, and biotin. They are questioning if they are dermarolling too aggressively and are willing to accept baldness if no improvement is seen in 6 months.

      community It's probably RU58841, which is weak in adenosine.

      in Treatment  14 upvotes 1 year ago
      The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.

      community Topical Finasteride - Affordable options

      in Finasteride/Dutasteride  4 upvotes 6 years ago
      The conversation discusses affordable options for topical Finasteride, including products like Morr F, 82F, and Essengen 6 Plus, with concerns about availability and cost. The user is seeking effective and convenient solutions, considering options like compounding pharmacies and homemade solutions.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community Are 10% fluridil formulations effective?

      in Treatment  6 upvotes 2 years ago
      The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

      community Mixing topical solutions: Morr F 10% and Loreal Seryoxil

      in Treatment  2 upvotes 3 weeks ago
      Mixing topical solutions like Morr F 10% (Minoxidil) and L'Oreal Seryoxyl (Stemoxydine) before application may not reduce their effectiveness. The goal is to apply treatments all at once instead of multiple times a day.

      community For real though, no side effects 2 months in dut (0.5mg) PO qAM

      in Satire  221 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically using dutasteride (0.5mg daily) with no side effects reported after two months. It also mentions the health benefits of one meal per day and the low incidence of side effects.