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      community Dutasteride results after 1 year and a few months

      in Progress Pictures  111 upvotes 8 months ago
      Switching from finasteride to dutasteride led to significant hair regrowth and thickening for the user, who also uses ketoconazole shampoo. The user experienced increased libido and encourages others not to be discouraged by negative opinions about dutasteride.

      community Mix topical finasteride with alfatradiol

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.

      community GT20029 phase II results release date?

      in Research/Science  16 upvotes 2 years ago
      The conversation is about the anticipated release date of phase II results for a hair loss treatment called GT20029 and the cautious optimism surrounding it due to past disappointments with similar treatments. Users expect an update in the next few months.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 2 years ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 5 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community 1.25mg Finasteride (6times a week)

      in Finasteride/Dutasteride  3 upvotes 4 months ago
      A 25-year-old is using 1.25mg finasteride six times a week and 5% topical minoxidil daily for hair loss. They are experiencing reduced libido and erectile issues, possibly due to stress, and are questioning if the finasteride dosage is affecting DHT suppression.

      community 6 month transformation from fin to dut+min+ru

      in Progress Pictures  102 upvotes 6 months ago
      A 30-year-old male switched from finasteride to a combination of dutasteride, oral minoxidil, and RU58841, achieving significant hair growth without side effects. He plans to add GHK-Cu peptide to his regimen for further improvement.

      community Dutasteride 1mg or RU58841 8% or topical Dutasteride

      in Treatment  3 upvotes 1 year ago
      The discussion focuses on hair loss treatments, with suggestions to increase oral Dutasteride to 1 mg or more, as topical Dutasteride is less effective. Other treatments mentioned include RU58841, Minoxidil, and dermastamping, with some users recommending injectable mesotherapy and topical Finasteride.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  4 upvotes 3 months ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

      community Topical Finasteride: 130 Day Update

      in Finasteride  8 upvotes 6 years ago
      The user tried a home-brew topical finasteride regimen for 120 days with initial benefits but no long-term improvement, leading to continued hair shedding. They switched to oral finasteride, experiencing mild testicle discomfort but no changes in libido or erections, and plan to continue this regimen for 120 days.

      community Does finasteride decrease free testosterone?

      in Research/Science  186 upvotes 1 year ago
      Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

      community Have we become too obsessed with DHT??

      in Chat  12 upvotes 5 years ago
      Focus on scalp health, not just DHT suppression, is crucial for hair regrowth. Effective treatments include Hair Restoration shampoo, LLLT laser cap, microneedling, and topical finasteride.

      community Wouldn’t this nuclear stack make it almost impossible to lose hair?

      in Research/Science  67 upvotes 11 months ago
      The conversation discusses a hair loss treatment regimen involving dutasteride, pyrilutamide, oral minoxidil, and microneedling, with the aim of suppressing DHT and stimulating hair growth. Users debate the effectiveness and potential side effects of these treatments, noting that individual results may vary and that no treatment is foolproof.

      community DUPA hair loss - What's the real deal ?

      in Research/Science  10 upvotes 3 years ago
      A 25-year-old male with DUPA (diffuse thinning including the donor area) has not seen improvement after 14 months on finasteride. He's considering switching to dutasteride (DUT) after advice from a hair loss YouTuber and is also contemplating trying RU58841.

      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community M22 Almost 3 months into treatment

      in Progress Pictures  131 upvotes 6 months ago
      A user shared progress pictures after almost 3 months of using dutasteride, minoxidil, stemoxydine, and tretinoin for hair loss, reporting positive results and no significant side effects. The user chose dutasteride over finasteride due to early balding and noted benefits like better skin and increased libido.

      community DUT/FIN FOR 20YR OLD + PERSONAL STORY

      in Finasteride/Dutasteride  9 upvotes 6 years ago
      A 20-year-old is experiencing severe hair loss and is considering using dutasteride and finasteride, worried about potential side effects. They feel depressed and isolated due to hair loss, and are exploring options like hair transplants and hair systems but are hesitant about faking it.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  16 upvotes 4 months ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.