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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Should I get transplant #4 or just shave my head?

      in Transplants  171 upvotes 1 year ago
      A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

      community Low iron and hair loss connection

      in Female  16 upvotes 1 year ago
      A 39-year-old woman noticed hair thinning and found she has an iron deficiency, which may be linked to hair loss. Suggestions included seeing a dermatologist, using spironolactone, and minoxidil.

      community Does everything that reduces DHT block 5ar?

      in Treatment  47 upvotes 1 year ago
      Finasteride is the most effective treatment for reducing DHT and addressing hair loss compared to fish oil and saw palmetto. Topical treatments like RU58841 and minoxidil are also discussed, but finasteride remains the most effective option.

      community Breaking hair loss news! GT20029 is a resounding success!

      in Product  132 upvotes 1 year ago
      GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

      community What do you think Jerry Seinfeld did to restore his hair?

      in Satire  940 upvotes 2 years ago
      The conversation speculates on how Jerry Seinfeld might have improved his hair appearance, suggesting various methods like hair styling, hair products, Minoxidil, Finasteride, and hair restoration, but no consensus is reached. Some comments are jokes, not serious suggestions.

      community Bryan Johnson just dropped his anti hair loss formula

      in Treatment  341 upvotes 2 years ago
      Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

      community 2.5 months topical minoxidil Progress

      in Progress Pictures  443 upvotes 2 years ago
      The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.

      community A Complete Guide to Hair Loss for Beginners

      in Research/Science  523 upvotes 2 years ago
      The conversation is a guide on treating hair loss, discussing finasteride and dutasteride to lower DHT, minoxidil for growth, ketoconazole shampoo for scalp health, and dermarolling for regeneration. RU58841 is mentioned as a DHT blocker but not recommended due to safety concerns.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community C’est terrible - at my wits end

      in Female  450 upvotes 2 years ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community My Story + Products other than Finasteride and Minoxidil that saved me

      in Finasteride/Dutasteride  25 upvotes 2 years ago
      A user shared their hair loss journey, starting at age 18 and leading to depression and insecurity. They found improvement with finasteride and minoxidil after two years, and also recommended products like Mielle Rosemary Mint Growth Oil, Mielle Organics Rosemary Mint Strengthening Hair Masque, Kevin Murphy Hair Resort Spray, Brooklinen Silk Pillowcases, and It's a 10 Keratin Leave in Conditioner for maintaining hair quality.

      community Does anyone here use everything except Fin

      in Minoxidil  23 upvotes 2 years ago
      The conversation is about hair loss treatments, specifically Minoxidil (Min) and Finasteride (Fin). The original poster is considering using Min and other treatments but is hesitant about Fin, while the responses vary, with some advocating for early use of Fin and others warning about potential side effects.

      community Are there ever going to be any oral DHT blocking treatments in the future?

      in Product  6 upvotes 2 years ago
      The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

      community Help with female pattern baldness

      in Female  9 upvotes 2 years ago
      A user discusses their struggle with female pattern baldness, mentioning that Minoxidil helped initially but their hair health declined after stopping a specific diet. They seek advice on managing oily, brittle hair and mention using an egg yolk and olive oil mixture as a temporary solution.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 2 years ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community Can someone explain the Dutasteride hysteria in this community?

      in Finasteride/Dutasteride  58 upvotes 2 years ago
      The conversation is about the double standard in the hair loss community regarding shedding when using different treatments. The conclusion is that shedding is considered normal when starting finasteride or minoxidil, but not when starting dutasteride, despite the fact that dutasteride is more effective at reducing DHT.

      community How to BECOME a RESPONDER to Fin/Dut if you are not responding

      in Finasteride/Dutasteride  306 upvotes 2 years ago
      The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.