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      community Can we all agree that PP405 is now 4 years away

      in Chat  95 upvotes 10 months ago
      PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.

      community My experience fighting hairloss for 2 years

      in Chat  6 upvotes 10 months ago
      The person experienced worsening hair loss despite using minoxidil, finasteride, and dutasteride. They are considering increasing dutasteride dosage, trying microneedling, RU58841, and oral minoxidil, and are advised to consult a trichologist.

      community What product does David Dobrik use

      in Chat  336 upvotes 10 months ago
      David Dobrik uses Minoxidil and possibly Finasteride for hair loss but applies them incorrectly. Users suggest he consider surgery due to his financial capability.

      community 3 year update - Dut, Min, Niz. 1.5mm roller

      in Progress Pictures  638 upvotes 10 months ago
      The user shared a 3-year hair restoration update using 0.5mg dutasteride daily, 5% minoxidil foam twice daily, a 1.5mm derma roller twice a month, and Nizoral shampoo. They reported significant improvement and maintenance of hair, with minimal side effects, and are satisfied with the results at age 40.

      community What is the ultimate hair regrowth protocol

      in Treatment  28 upvotes 10 months ago
      The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

      community Just Minoxidil 5% twice a day for 5 months

      in Progress Pictures  584 upvotes 10 months ago
      Significant hair regrowth was achieved using 5% Minoxidil twice daily and weekly microneedling with a 0.8 mm dermaroller over five months. Finasteride was not used due to concerns about side effects and availability in France.

      community Use minoxidil & finasteride. It works.

      in Minoxidil  555 upvotes 10 months ago
      Minoxidil and finasteride effectively improve hairlines and reduce balding, though some users report side effects like reduced libido. Consistent use over 1-2 years leads to significant hair regrowth, with some users also using skincare and biotin for added benefits.

      community Is 20 too young for Dut (or fin)?

      in Finasteride/Dutasteride  18 upvotes 10 months ago
      A 20-year-old is considering starting dutasteride or finasteride for hair loss, with concerns about potential side effects and development. Users shared experiences with both treatments, noting that finasteride is often the first step, while dutasteride may be more effective for some, and emphasized consulting a healthcare provider.

      community My final attempt at creatine with fin

      in Product  41 upvotes 10 months ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community Finasteride Price Report in Canada

      in Finasteride/Dutasteride  9 upvotes 11 months ago
      Finasteride prices in Canada vary, with Costco offering lower prices compared to smaller pharmacies, and no membership is needed to access their pharmacy. Users discuss the cost-effectiveness of oral versus topical treatments, with some preferring oral minoxidil and finasteride due to fewer side effects.

      community Rate Cbum hair transplant after 1 year

      in Transplants  444 upvotes 11 months ago
      The hair transplant has a straight, unnatural-looking hairline that many find unappealing. The person is not using finasteride or minoxidil, which may affect future hair retention.

      community Quit finasteride after 15+ years

      in Update  974 upvotes 11 months ago
      A user stopped finasteride after 15 years due to severe side effects, which improved after quitting. They maintained most of their hair and are considering alternatives like topical treatments or RU58841.

      community 5+ year users, what has your experience been on fin and dut?

      in Chat  30 upvotes 11 months ago
      Users discussed their experiences with hair loss treatments, primarily finasteride (Fin) and dutasteride (Dut), often combined with minoxidil (Min) and derma rolling. Many reported mixed results, with some seeing slowed hair loss and others experiencing side effects or minimal improvement.

      community Minoxidil works only with Retinoic acid

      in Minoxidil  317 upvotes 11 months ago
      Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.

      community Summary of future treatments from 2020

      in Chat  53 upvotes 11 months ago
      Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2263 upvotes 11 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community Oral Minoxidil- Be Careful!!!!!

      in Minoxidil  417 upvotes 11 months ago
      Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 11 months ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community Hairloss has destroyed my Life completely

      in Chat  339 upvotes 11 months ago
      A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 1 year ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community [30M] My Aggressive Hair Loss Protocol – 5 Years In, Still Full Coverage

      in Treatment  25 upvotes 1 year ago
      A 30-year-old man shares his successful hair loss protocol, which includes finasteride, Nizoral shampoo, low-level laser therapy, microneedling, and past use of oral minoxidil. He plans to consider dutasteride and possibly hair transplants in the future, while advising caution with crown transplants before age 35.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 1 year ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community Dutasteride absolutely nukes hair DHT

      in Finasteride/Dutasteride  486 upvotes 1 year ago
      Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  218 upvotes 1 year ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 1 year ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.