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      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  7 upvotes 3 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Turning vellus hairs into terminal hair

      in Research/Science  12 upvotes 1 year ago
      People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

      community 6 months progress after minoxidil/finasteride stopped working

      in Progress Pictures  19 upvotes 1 year ago
      A 24-year-old with male pattern baldness experienced side effects from oral finasteride and switched to a topical minoxidil/finasteride combination, later incorporating daily shampooing and scalp brushing to manage hair loss and dandruff. After initial shedding, the regimen led to reduced hair loss and new hair growth, with the user now using a densita mf combination (5% minoxidil/0.1% finasteride + redensyl) nightly.

      community 3 Doctors 3 Diagnoses: Please help.

      in Treatment  4 upvotes 2 years ago
      A user experiencing hair loss received three different diagnoses: androgenic alopecia, traction alopecia, and scarring alopecia, and tried treatments like minoxidil and finasteride without success. They are considering dutasteride but were advised to seek anti-inflammatory medication instead.

      community Aggressive diffuse thinning after 1 year of fin and min

      in Progress Pictures  7 upvotes 1 year ago
      The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.
      Help: Digital Perm while Thinning Hairline

      community Help: Digital Perm while Thinning Hairline

      in Basic Questions  142 upvotes 3 months ago
      A 20-year-old male experiencing hair loss is using finasteride for 8 months and is considering a digital perm but is concerned about potential hair damage, especially at the thinning hairline. Advice given includes continuing finasteride, using gentle hair products, and possibly trying topical minoxidil or CBD cream for scalp care.

      community Ultrasound can show you if your hair will ever grow back

      in Research/Science  41 upvotes 4 months ago
      Ultrasound imaging can non-invasively detect active and inactive hair follicles, inflammation, and fibrosis, potentially reducing unnecessary biopsies. It may help assess hair growth potential and diagnose scalp issues, but some users believe in trying treatments regardless of ultrasound results.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 4 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Redensyl for Hair Loss — What It Can and Can’t Do

      in Treatment  2 upvotes 7 months ago
      Redensyl is a plant-based treatment that may support hair regrowth by reactivating dormant follicles and improving hair density, especially in early-stage thinning. It is not a miracle cure and results vary; it is less proven than Minoxidil or Finasteride and may cause scalp irritation.

      community Minoxidil question

      in Minoxidil  41 upvotes 8 months ago
      Minoxidil is being questioned for its effects on surrounding hair when applied to a receding hairline. The user is concerned it might worsen the appearance by causing nearby hair to fall out.

      community Starting Finasteride After Being on Oral Minoxidil 19M

      in Minoxidil  4 upvotes 8 months ago
      A 19-year-old is using 2.5 mg oral minoxidil for hair loss and plans to add finasteride later, but is concerned about potential hair loss after starting finasteride. Others advise starting finasteride sooner to prevent further hair loss, noting that shedding is a normal part of the process.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 9 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community So what is the actual efficacy of topical minoxidil?

      in Research/Science  11 upvotes 11 months ago
      Minoxidil can stimulate hair growth but does not prevent long-term hair loss, while finasteride or dutasteride is necessary to address DHT and maintain hair. Family hair history may not predict individual outcomes, and combining treatments like microneedling can enhance results.

      community 18M Experiencing Shedding and Side Effects on Finasteride 0.25mg ED

      in General  115 upvotes 11 months ago
      An 18-year-old has been using minoxidil since March 2024 with good results but experienced sexual side effects from topical finasteride and oral finasteride, leading to stress and heavy hair shedding. They are concerned about the side effects of finasteride, potential initial shedding, and whether stopping finasteride will worsen hair loss.

      community RU 58841 or do I go for Nizoral shampoo instead? Have curly hair

      in Ketoconazole  1 upvotes 11 months ago
      The user is considering whether to add RU58841 or Nizoral shampoo to their current hair loss treatment of finasteride and minoxidil, noting budget constraints and concerns about hair dryness. They are unsure if RU58841 is worth adding or if they should use both treatments to see the effects.

      community Scalp inflammation let’s talk about it?

      in Chat  11 upvotes 1 year ago
      Scalp inflammation can cause hair thinning and may be related to diet, infections, or conditions like psoriasis. Treatments suggested include using Nizoral shampoo and checking vitamin levels.