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      community Hair shed after adding tretinoin with topical minoxydil

      in Minoxidil  3 upvotes 1 year ago
      Adding tretinoin to a minoxidil routine can cause initial hair shedding, which may be normal as it potentially increases minoxidil's efficacy. Users suggest being cautious with tretinoin application, especially around microneedling, to avoid increased systemic absorption.

      community For those dealing with an unbearable scalp itch/pressure/inflammation.

      in Treatment  8 upvotes 6 years ago
      The conversation discusses using cetirizine (Zyrtec) topically to relieve scalp itch associated with hair loss and suggests it may also benefit androgenetic alopecia (AGA). One person found relief from scalp itch after three months on finasteride, noting the itch was linked to areas where hair was lost.

      community Connection between finasteride and nafld?

      in Research/Science  4 upvotes 1 year ago
      Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

      community Pyrilutamide - your experience?

      in Product  12 upvotes 3 years ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community Losing hairs on aggressive treatment.

      in Transgender  2 upvotes 1 month ago
      The user is experiencing hair loss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.

      community Thoughts on this product or other suggestions?

      in Product  12 upvotes 9 months ago
      The conversation discusses various hair loss treatments, including minoxidil, finasteride, latanoprost, tretinoin, dutasteride, and cetirizine, with concerns about effectiveness, cost, and potential side effects. Users express skepticism about the product's price and the combination of multiple compounds.

      community How much do we know about PTD-DBM?

      in Question  7 upvotes 8 years ago
      PTD-DBM is a Korean-developed treatment for hair loss, with limited information available and some users testing it personally. A user purchased PTD-DBM for $115 and plans to test it on their temples, but its effectiveness and authenticity remain uncertain.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Best tretinoin strength with minoxidil ?

      in Treatment  2 upvotes 2 months ago
      The conversation is about using topical tazarotene with minoxidil for hair loss treatment. A user suggests using a lower strength than 0.025% for daily application.

      community Bad doctors even in the USA

      in Transplants  170 upvotes 6 years ago
      Young men are advised to delay hair transplants until after age 25, using finasteride, minoxidil, and dermarolling to manage hair loss. Concerns about unethical doctors highlight the need for careful planning.

      community Why is there more skepticism in RU than Pyrilutamide?

      in Chat  12 upvotes 3 years ago
      The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

      community Hormone tests to decide on oral fin

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

      community Topical - Lantoprost .01%, MIN 10% DUT .05%, Hydrocortisone 1% Progrestron .025%

      in Treatment  6 upvotes 10 months ago
      A user was prescribed a topical treatment for hair loss including Latanoprost, Minoxidil, Dutasteride, Hydrocortisone, and Progesterone, after using an oral Minoxidil and Finasteride combo without significant results. Concerns were raised about the long-term use of hydrocortisone, with suggestions to consult a doctor regularly.

      community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

      in Research/Science  7 upvotes 3 years ago
      The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 8 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  218 upvotes 1 year ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Whats the safety Profile for Breezula?

      in Treatment  6 upvotes 5 years ago
      The conversation is about the safety of Breezula compared to RU58841 for hair loss treatment. The user believes Breezula is safer but less effective than RU58841.

      community Bicalutamide effect on androgens?

      in Treatment  4 upvotes 5 years ago
      Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  44 upvotes 4 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community Creatine made all my high DHT symptoms return

      in Research/Science  81 upvotes 1 year ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community Is regrowth on an androgen receptor blocker possible?

      in Chat  11 upvotes 2 years ago
      RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.