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      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 2 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community 5mg KX 826 Worked. Will 2.5mg Hold?

      in Technology  6 upvotes 11 months ago
      Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.

      community important questions about RU58841

      in Research/Science  3 upvotes 2 years ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.

      community Can Pyrilutamide use stopp Minoxidil gains

      in Chat  3 upvotes 2 years ago
      The conversation discusses whether using pyrilutamide would interfere with minoxidil's ability to regrow hair, considering pyrilutamide is seen as a maintenance drug that stops shedding, while minoxidil promotes hair growth but causes initial shedding.

      community 4 month progress on treatment! Low dose fin.

      in Progress Pictures  179 upvotes 1 year ago
      User shared 4-month progress on hair loss treatment using 0.25mg finasteride daily and topical minoxidil daily, noting cognitive decline possibly linked to finasteride. Users discussed side effects, alternative treatments, and shared similar experiences.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  15 upvotes 3 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 2 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community Rate my treatment stack from 1-10

      in Chat 1 year ago
      The conversation discusses various hair loss treatments, with a focus on pyrilutamide, minoxidil, and alternatives to finasteride due to intolerance. Users suggest adding a DHT blocker like finasteride or dutasteride, and some recommend trying topical versions to reduce side effects.

      community Does Fluridil even work? (Eucapil)

      in Treatment  7 upvotes 4 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil's effectiveness is questioned due to unconvincing clinical trial and lack of FDA approval.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 3 weeks ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community Kintor 0.9% , save your money friends

      in Minoxidil  9 upvotes 3 weeks ago
      Kintor 0.9% is not effective for hair regrowth or thickening and may cause testicle sensitivity. The conversation criticizes the hype around Kintor and discusses the ineffectiveness of pyrilutamide compared to other treatments like RU58841, finasteride, and minoxidil.

      community Pyrilutamide - one month update

      in Update  14 upvotes 3 years ago
      User on 5th week of Pyrilutamide and oral Minoxidil, no hair loss improvement yet. Others suggest waiting 3 months for results.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.