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      community Where the fuck are the pyrilutamide GB guys?

      in Chat  23 upvotes 4 years ago
      The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

      community About GT20029's Efficacy and Strength

      in Chat  7 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community The New, Improved CB-03-01/Setipiprant Group Buy

       27 upvotes 9 years ago
      The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 6 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.

      community Bad news about GT20029 from Anagen Inc

      in Treatment  11 upvotes 3 years ago
      The conversation is about the difficulty in obtaining GT20029, a hair loss treatment, due to patent issues and the need to resort to group buys or Chinese labs for acquisition. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 1 year ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 2 years ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  16 upvotes 2 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

      community Where to buy setipiprant from ?

      in Treatment  2 upvotes 1 year ago
      The conversation is about hair loss treatments, specifically setipiprant, which the user is considering after experiencing side effects from finasteride and dutasteride. Another user mentions that setipiprant was ineffective in clinical trials.

      community Does Tretionin make minoxidil work better?

      in Minoxidil  9 upvotes 1 year ago
      Tretinoin may enhance the effectiveness of minoxidil for some users, though experiences vary. Some users report better results with oral minoxidil compared to adding tretinoin.

      community Tretinoin and Minoxidil effectiveness

      in Research/Science  10 upvotes 9 months ago
      Tretinoin may enhance minoxidil absorption, potentially improving hair regrowth when combined with microneedling. Users discuss various treatments like minoxidil, finasteride, dutasteride, and microneedling, with mixed results and concerns about side effects and scarring.

      community Pyrilutamide - cosmetic vs. clinical trials

      in Treatment  3 upvotes 6 months ago
      The conversation discusses the difference between the commercially available Pyrilutamide and the version in clinical trials. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community Reputable place to buy Clascoterone?

      in Product  2 upvotes 2 months ago
      The conversation is about finding a reputable place to buy Clascoterone in the US. An alternative treatment, pyrilutamide, is suggested as a strong and official option.

      community Tretinoin for increased minoxidil conversion

      in Research/Science  11 upvotes 4 years ago
      The conversation is about using Tretinoin with Minoxidil for hair loss treatment, discussing the effectiveness and personal experiences with different concentrations. The image linked in the post received negative reactions for being unpleasant.

      community What do we currently know about clascoterone?

      in Chat  5 upvotes 5 months ago
      Clascoterone is seen as a promising topical treatment for hair loss, similar to finasteride but without side effects, though concerns exist about its long-term effectiveness. Other treatments discussed include topical minoxidil, ketoconazole, microneedling, and oral options like dutasteride and minoxidil.

      community The urge to buy Clascoterone 5% solution

      in Research/Science  11 upvotes 6 months ago
      Clascoterone 5% solution is not yet commercially available, with only the 1% solution currently sold for acne. Users discuss the potential of Clascoterone as a hair loss treatment, comparing it to other anti-androgens like RU58841 and Eucapil.

      community Winlevi (clascoterone) for hairloss?

      in Treatment  1 upvotes 11 months ago
      Winlevi (clascoterone), a DHT blocker, is being considered for hair loss treatment, though it's primarily an acne medication. Users discuss its potential effectiveness and note it may only work for a short time.

      community Topical Dutasteride - Dosage / Frequency (Strut gel formulation)

      in Treatment  16 upvotes 5 years ago
      A user ordered a topical dutasteride gel with tretinoin for hair loss after unsatisfactory results with minoxidil and finasteride. Another user shared their experience with the same product, noting its pleasant smell and feel but difficulty in application and uncertainty about its absorption and frequency of use.

      community Estimate of GT20029 on the grey market?

      in Technology  9 upvotes 2 years ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 3 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Question about clascoterone acne cream

      in Treatment  2 upvotes 2 months ago
      Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 9 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community Personal experiment: tretinoin and diffuse thinning

      in Treatment  9 upvotes 3 years ago
      User experienced hair growth with finasteride and minoxidil, but after using tretinoin, faced aggressive thinning and hair loss. They plan to stop tretinoin for two months to see if the problem improves.