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community Clascoterone is the way to go if you cannot use DHT blockers

in Chat 11 upvotes 1 month ago

Clascoterone is suggested as an alternative for those who experience side effects from finasteride and dutasteride. It is not widely available yet, but some users are obtaining it from compounding pharmacies or suppliers like Echemi.

community 5 months progress on only daily finasteride 1.25mg

in Update 113 upvotes 1 year ago

OP has been using daily oral finasteride 1.25mg for 5 months with noticeable progress and no side effects. They chose this dosage by cutting 5mg pills into quarters due to cost.

community There is news from pyrilutamide?

in Product 32 upvotes 2 years ago

The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

community Tfw you’ve been swallowing dut for 6 months and your hair still looks like a mangled birds nest

in Satire 401 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, and dutasteride, with mixed results and suggestions for combining treatments or considering hair transplants. Some users experience no improvement or side effects.

community So is this the actual trial results for pp405?????

in Research/Science 92 upvotes 2 months ago

PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

community Duastride 0.5 mg Side Effects: Should I Switch to Finasteride?

in Treatments 53 upvotes 7 months ago

OP experienced erectile dysfunction after taking a 0.5 mg dutasteride capsule for hair loss and is considering switching to finasteride. A user suggested consulting a dermatologist and possibly trying topical treatments if side effects persist.

community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

in Treatment 30 upvotes 5 months ago

A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 2 years ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community What are some promising/revolutionizing treatments that are in the pipeline/currently available?

in Treatment 4 upvotes 1 year ago

The conversation discusses various hair loss treatments, including pyrilutamide, RU58841, topical dutasteride, oral minoxidil, and oral finasteride/dutasteride. It also mentions potential treatments like PP405, Verteporfin, GT20029, and AMP303.

community my Body hair has stopped working

in Finasteride/Dutasteride 44 upvotes 2 years ago

A user on dutasteride for hair loss noticed hair regrowth on their head but a significant reduction in body hair growth. They plan to switch to finasteride and dutasteride and are considering testosterone replacement therapy but are concerned about its effects on hair growth.

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