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810-840 / 1000+ resultscommunity The Effect of Intradermal Botox on Androgenetic Alopecia and Its Possible Mechanism (Journal of the American Academy of Dermatology (2020)
Intradermal botulinum toxin (BTX) injections effectively treat androgenetic alopecia (AGA) by inhibiting TGF-β1 secretion from hair follicles. Further research and long-term follow-up are needed to confirm these findings.
community Is Scalp DHT more important than Serum DHT?
The user lost ground on oral finasteride and plans to switch to topical finasteride/minoxidil and microneedling. They are curious if topical treatments are more effective than oral ones.
community Selling KY19382 powder a novel activator of Wnt/β-catenin signaling
The conversation is about selling KY19382 powder, a novel activator of Wnt/β-catenin signaling, and Kolliphor EL liquid for vehicle formulation. The seller offers worldwide shipping.
community Saw this apparent study on twitter. Thoughts?
A mixture of MSM, kombucha, and black tea was applied topically for hair growth in mice. The conversation suggests skepticism about translating these results to humans.
community 24 - Thinning: Fina + Mino or Shave?
community High estradiol from finasteride
community My hair has been thin since I was a kid - is a transplant the only way?
The user has been using HIMS chewable for two months to address lifelong thin hair. They are considering a hair transplant as a potential solution.
community Q1/Q2 Exciting times ahead - hope!
The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.
community DUPA, Non Responders and Connective Tissue Disorders
A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.
community Interpreting pre-finisteride blood panels
The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.
community Almost 4 months on GHK-Cu hair growth progress
OP noticed fuller and thicker hair after almost 4 months of using GHK-Cu, a copper-binding peptide, through subcutaneous injections. Some users were skeptical, questioning the authenticity and potential commercial intent behind the post.
community Questions about DUPA and figuring out what my hairloss is (NEED INPUT BADLY)
The conversation discusses severe hair shedding and thinning, with the original poster using finasteride, oral minoxidil, and other supplements without improvement. The discussion highlights the possibility of telogen effluvium and the importance of addressing potential underlying health issues, such as stress and gut health, rather than assuming diffuse unpatterned alopecia (DUPA).
community is this regrowth or maintenance or loss? 4 months difference
The user experienced noticeable hair regrowth after using finasteride for 2 years, oral minoxidil for 1 year, and recently starting dermarolling. The right temple shows significant improvement, while the left remains similar.
community 5 months in Hims 2 in 1 fin/min derma roller 1.5
A user shared progress pictures after 5 months using Hims 2-in-1 finasteride and minoxidil with a 1.5mm derma roller. Other users commented positively and shared their own experiences with the treatment.
community Pyrilutamide or RU Monotherapy?
Using Pyrilutamide or RU as monotherapy for hair loss? Share experiences.
community blood DHT levels shot up after doubling dutasteride dosage
A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.
community 3.5 year (December 2022 - March 2026) difference after much prior struggle. Winning the war?
The user shared their successful hair regrowth journey using a combination of oral Dutasteride and a topical mix of Finasteride, Minoxidil, Tretinoin, and Ketoconazole. They experienced no side effects and noted significant improvement, except for one persistent thinning area.
community Counter-update: Cbum's transplant DOESNT look super good now
Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.
community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways
Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.
community How life feels after replying to fin/dut
community Am I seeing regrowth/thickening here? Started meds november new photo today
The user started oral finasteride, switched to oral dutasteride, oral minoxidil, and microneedling, and is seeing potential hair thickening. Others agree there is regrowth and suggest continuing treatment.
community dermaroller or dermastamp?? which one is better
People discussed which is better for hair loss treatment between a dermaroller and a dermastamp, concluding that a dermastamp is better. They also mentioned that a dermaroller can be used for beard growth.
community Fin ED is primarily blood flow related, not hormonal as such - a theory
The conversation discusses the theory that finasteride-induced erectile dysfunction (ED) is related to blood flow rather than hormonal changes. The user suggests that lowering LDL cholesterol aggressively might improve ED symptoms for those on finasteride.
community China clinics pushing “PT88/PT66 / SP88/SP66 mesotherapy ampoules” + I have seb derm — anyone heard of this / any evidence?
The user is exploring hair loss treatments in China, currently using finasteride and minoxidil, and is concerned about seborrheic dermatitis. Clinics are recommending selenium sulfide, doxycycline, and mesotherapy ampoules like PT88/PT66 or SP88/SP66, but the user is unsure about their effectiveness.
community Mechanism of action of alfatradiol (17 alpha estradiol)
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
community HairCafe was right about trolls on dutasteride
A user falsely claimed to use 2.5mg of dutasteride by using someone else's photo, which actually showed results from finasteride. The conversation discusses the challenges and skepticism around hair loss treatments like dutasteride and finasteride.
community My theory is that combining pyrilutamide with alfatrodial could be similar in efficacy to finasteride.
Combining pyrilutamide and alfatradiol might be as effective as finasteride for hair maintenance. The user plans to try this combination alongside minoxidil and keto shampoo, hoping for improved hair thickness.
community Is my friend lying about getting a transplant?
A person suspects their friend had a hair transplant instead of stem-cell injections due to a noticeably straight hairline. The discussion includes opinions on hair transplants, societal perceptions, and suggestions like using finasteride to maintain hair.
community CB-03-01 / Breezula Personal Results
The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.