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      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Has anyone had luck with low-level laser therapy (LLLT) devices?

      in Question  5 upvotes 7 years ago
      Low-level laser therapy (LLLT) devices may help thicken existing hair but are not effective for regrowing hair on bald areas. Users suggest sticking with finasteride, minoxidil, and dermapenning, as LLLT devices like Capillus are expensive and results are mixed.

      community Is PP405 gonna flop or what???

      in Research/Science 2 months ago
      PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hair follicles, many believe it won't replace hair transplants or significantly outperform current options.

      community Status update on upcoming treatments

      in Technology  44 upvotes 6 months ago
      Current treatments for hair loss include finasteride, minoxidil, and derma rolling. New treatments like Breezula, PP405, and others are not expected until at least 2027 or later.

      community When is the cure gonna drop , how much more time

      in Research/Science  112 upvotes 3 months ago
      There is no imminent cure for hair loss, but treatments like Minoxidil, Finasteride, and new drugs such as KX-826, GT-20029, and PP405 are being explored. Current solutions focus on slowing hair loss and stimulating growth, with hopes for better options in the future.

      community Why do the mice always win????

      in Research/Science  25 upvotes 11 months ago
      A new stem cell therapy shows promise in treating hair loss, but skepticism remains about its availability. Users humorously discuss the effectiveness of treatments on mice compared to humans.

      community What’s the go with verteporfin?

      in Technology  9 upvotes 2 years ago
      The conversation discusses using verteporfin for hair regrowth and minimizing scarring after hair transplants. Some individuals plan to self-administer verteporfin, potentially in combination with microneedling, as an alternative to hair transplants.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Regenera Activia stem cells vs Exosomes (Cellgenic)?

      in Treatments  32 upvotes 10 months ago
      The conversation discusses the effectiveness of Regenera Activia stem cells versus Cellgenic exosomes for hair loss treatment. The user has been using topical minoxidil 5% and 0.001% estradiol for a year without results.

      community DIY do it yourself prp, meso and other crazy procedures.

      in Technology  2 upvotes 2 years ago
      The conversation discusses DIY cosmetic procedures like PRP, mesotherapy, and micro-needling, with some users experimenting with Minoxidil, finasteride, and RU58841 for hair loss. It highlights a community of mostly older women performing these treatments themselves.

      community How is no one talking about this?

      in Treatment  6 upvotes 1 year ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Did anyone tried exosome therapy

      in Treatment  1 upvotes 1 year ago
      Exosome therapy for hair loss is questioned for its effectiveness and authenticity. Users express skepticism, citing manipulated photos and high costs.

      community Are we still getting the PP405 phase 2a results by the end of March?

      in Research/Science  27 upvotes 3 months ago
      People are discussing the anticipated release of PP405 phase 2a results, expected by the end of March, with some skepticism about its effectiveness. There is cautious optimism due to past experiences with similar treatments like Breezula, despite concerns about the lack of presentation at the AAD 2026 conference.

      community can someone help me identify these pls

      in Treatment 6 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community Is the clinic diagnosis legit to you ?

      in Transplants  1 upvotes 1 year ago
      The clinic diagnosed the user with NW3 and AGA, noting thinning hair despite using finasteride for 3 years, and suggested PRP and Mesotherapy before considering a transplant. The user questions the necessity of these treatments without confirming retrograde alopecia and its treatability.