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      community 8 week - sharing Finasteride blood test update

      in Progress Pictures  6 upvotes 2 years ago
      A 32-year-old male started taking 0.5mg of finasteride daily for hair thinning and, after 8 weeks, experienced a 70% reduction in DHT and an increase in estradiol; he is currently in the shedding phase of treatment and questioning if the dosage is correct based on his DHT levels. He began with a lower dose due to already low normal testosterone and DHT levels.

      community The Breezula 539% headline is doing a lot of heavy lifting right now.

      in Research/Science  14 upvotes 1 month ago
      Breezula shows promising results for hair loss, with one trial showing a 539% improvement and another 168%, but lacks combination data with treatments like minoxidil or dutasteride. Its mechanism differs from finasteride, potentially offering fewer side effects by blocking receptors locally at the follicle.

      community Severe diffuse thinning since 13 years old

      in Treatment  6 upvotes 1 year ago
      A 15-year-old experiencing severe diffuse thinning plans to use minoxidil, dermarolling, and possibly ketoconazole, with hopes to later incorporate finasteride. Concerns about starting finasteride too young and the need for a dermatologist consultation are discussed.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community My (26m) Progress on 0.5mg Fin and 5% Topical Min

      in Progress Pictures  75 upvotes 2 months ago
      A 26-year-old male shares his progress using 0.5mg finasteride and 5% topical minoxidil for hair loss, considering transitioning to 3mg oral minoxidil. He is also contemplating using a hair system to boost confidence while continuing treatment.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community 3 year progress pics- minoxidil/dutasteride/PRP

      in Progress Pictures  117 upvotes 2 months ago
      The user shared their 3-year hair loss treatment progress using dutasteride, minoxidil, PRP, micro-needling, and vitamin D supplements, noting improvements and no side effects. They also discussed transitioning from finasteride to dutasteride and increasing minoxidil dosage, while considering the effectiveness of PRP and micro-needling with long hair.

      community Me looking at my friends slight temple recession and calculating how long it'll take for him to bring it up to me, the Hairloss expert (I've been on finasteride for 6 months) so I can slap him with a 30 minute presentation about DHT miniaturization and 5-alpha reductase inhibitors

      in Satire  536 upvotes 2 years ago
      The post is a humorous take on the author's experience with hair loss and using finasteride for six months. The conversation includes discussions about hair loss, treatments like finasteride, and personal experiences with baldness.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community FOR PYRILUTAMIDE NON-BELIEVERS (progress album, 14 months)

      in Progress Pictures  30 upvotes 2 years ago
      A user shared their 14-month progress using Pyrilutamide and Minoxidil for hair loss, noting improvement and no side effects with these treatments, unlike their negative experiences with Finasteride and RU58841. They emphasized the importance of consistent application for seeing results.

      community Switching between topical(10%) and oral(2.5mg)

      in Minoxidil  3 upvotes 11 months ago
      The user is considering switching between topical minoxidil (10%) and oral minoxidil (2.5mg) to manage hair shedding around the temples, while also using a dermaroller and biotin. They are concerned about the potential side effects of oral minoxidil, such as hypertrichosis, and the impact on hair shedding if they stop using it.

      community Has anyone experienced burning scalp after chemical damage (perm)?

      in Chat  6 upvotes 9 months ago
      A user experienced burning, itching, and soreness on their scalp after a perm in 2021, despite using oral finasteride, oral minoxidil, and ketoconazole shampoo. They are seeking advice on whether to pursue further medical tests or consult a neurologist for nerve pain.

      community 6 months on topical dut (album linked)

      in Progress Pictures  24 upvotes 4 years ago
      The post and conversation are about a user's 6-month progress using topical dutasteride, 8% minoxidil, tretinoin, 2% ketoconazole shampoo, microneedling, oral finasteride, pumpkin seed oil, Vitamin D3, a men's multivitamin, rosemary oil, and 5% minoxidil foam for hair loss treatment.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community 4 month update - nuclear stack, 42m

      in Progress Pictures  256 upvotes 1 year ago
      A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

      community 1.5 Year - Bad Results (HT, FIN, MINO, PRP, etc)

      in Progress Pictures  66 upvotes 1 year ago
      A user shared their disappointing results after 1.5 years of hair treatments, including a hair transplant, finasteride, minoxidil, PRP, vegan shampoo, and more. They are considering switching to dutasteride, oral minoxidil, and improving their microneedling routine.

      community Fin year 3 results/maintainence

      in Progress Pictures  332 upvotes 1 year ago
      A user has used finasteride for three years to maintain hair thickness and is considering adding minoxidil for temple recession. They report no side effects and are satisfied, while others discuss minoxidil's pros and cons and share hair treatment experiences.

      community Thoughts on my Topical and Oral concept idea ?

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice on improving their hair loss treatment regimen, considering changes to their topical solution, and is curious about others' daily routines and recommendations for medications and supplements. They are contemplating switching Tretinoin for Tazarotene, Latanoprost for Bimatoprost, and possibly adding Alfatradiol, Topical Melatonin, or a topical androgen receptor antagonist.