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community One month Umbrella Labs PP405 results.

in Progress Pictures 56 upvotes 4 months ago

The user tried a product labeled as PP405 from Umbrella Labs for hair loss but saw no changes, and it was revealed to be a fake or misidentified product. The user is also using finasteride, minoxidil, and other treatments but is still experiencing hairline issues.

community Topical Fin 0.3/Min 6% - 11 Week progress.

in Progress Pictures 82 upvotes 9 months ago

The user applied topical finasteride 0.3% and minoxidil 6% once daily, used keto shampoo weekly, and derma stamped weekly or biweekly. They noticed hair improvement, possibly due to regrowth or letting it grow longer.

community Can we get a reality check on PP405?

in Research/Science 83 upvotes 5 months ago

PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

community Should topicals be massaged thoroughly into the scalp ?

in Minoxidil 5 upvotes 1 year ago

Topicals like minoxidil and finasteride should reach the scalp, but excessive massaging can cause hair to fall out. The evaporation felt is likely the carrier substances like alcohol or propylene glycol.

community PP405 Phase 2a press release with early results

in Research/Science 696 upvotes 9 months ago

PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

8 upvotes 6 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Do i have to worry about mixing these ingredients with Finasteride?

in Treatment 5 years ago

The user is concerned about mixing Pantostin (with Alfatradiol) and Finasteride in a topical solution, fearing a potential toxic reaction or ineffectiveness. They seek advice on whether this combination is safe.

community Any experience with topical minoxidil with tretinoin around toddlers

in Minoxidil 2 months ago

Concerns about using topical minoxidil with tretinoin around toddlers due to potential exposure. Some suggest using oral minoxidil instead to avoid risks.

community 1.25 mg of both loniten and finasteride since 9/18/25

in Progress Pictures 5 upvotes 1 week ago

The user has been using 1.25 mg of oral minoxidil and finasteride since September 2025 to address diffuse hair thinning, and is considering trying a new shampoo. Other users suggest increasing the minoxidil dose and trying dutasteride.

community I wrote a poem about pp405 (potential treatment)

in Satire 19 upvotes 1 year ago

A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

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