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community Cigarette smokers had increased serum levels of DHT 14% higher than non smokers.

in Chat 82 upvotes 3 years ago

The effects of smoking cigarettes on DHT levels and its potential effect on hair loss, with some people sharing experiences in relation to their own hair loss. Various treatments for reducing or reversing hair loss were discussed, such as quitting smoking, minoxidil, finasteride and RU58841.

community 20MTF Results on the crown from 1 year on estrogen injections

in Transgender 468 upvotes 4 months ago

Estrogen injections significantly improved hair growth, particularly on the crown, after stopping finasteride. Monotherapy with estrogen led to hairline improvement, but also caused sterility and potential feminization effects.

community Low Testosterone after taking finastreide

in Finasteride 45 upvotes 1 year ago

A 19-year-old experienced significantly low testosterone levels after one month of taking finasteride. Suggestions included checking test units, retesting, and exploring other potential causes.

community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning

in Finasteride/Dutasteride 7 upvotes 1 year ago

An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.

community Aggressive diffuse thinning after 1 year of fin and min

in Progress Pictures 7 upvotes 1 year ago

The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

community Pyrilutamide at 16 years old- update 2

in Research/Science 21 upvotes 3 years ago

A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

community Binding affinity does not equal potency for anti androgens? Comparing pyrilutimide to cb-03-01

in Research/Science 7 upvotes 3 years ago

Pyrilutimide and CB-03-01, two treatments for hair loss, have similar clinical trial results despite different binding affinities to androgen receptors. Factors other than binding affinity, like the time a drug stays bound to the receptor, may influence their effectiveness.

community Ru58841 stops seb derm ( the itching)?

in Treatment 8 upvotes 2 years ago

RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.

community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

in Transgender 591 upvotes 2 years ago

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

community 9 months on Finasteride 1,25mg + HRT

in Transgender 15 upvotes 2 years ago

The conversation is about the results of using hormone replacement therapy (HRT) with estrogen and finasteride for hair loss, and switching from finasteride to bicalutamide as an anti-androgen treatment. The user shared before and after photos to discuss the effectiveness of these treatments.

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