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      community I fought the reaper, and won!!

      in Progress Pictures  1022 upvotes 1 year ago
      A user shared their successful hair regrowth journey using oral minoxidil, dutasteride, and eucapil, with additional benefits from MTF hormone replacement therapy. They advised consulting specialists and considering individual responses to treatments.

      community 2 years on treatment (stack update)

      in Progress Pictures  461 upvotes 1 year ago
      A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

      community How good are anti-androgens? Are they worth seeking?

      in Research/Science 2 months ago
      The conversation discusses hair loss treatments, including dutasteride, oral minoxidil, finasteride, and potential additions like topical finasteride, minoxidil, micro-needling, and topical anti-androgens such as RU58841. The effectiveness and worth of these treatments, including localized dutasteride mesotherapy, are considered.

      community Is RU58841 or pyrilutamide a stronger topical anti-androgen?

      in Treatment  3 upvotes 4 months ago
      The conversation discusses adding either RU58841 or pyrilutamide to a hair loss treatment regimen that already includes oral dutasteride and oral minoxidil. RU58841 is considered the stronger anti-androgen but may have more side effects.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 7 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.

      community Temple regrowth, 5 months on fin + min

      in Progress Pictures  233 upvotes 3 months ago
      A trans man shared his 5-month progress using finasteride and minoxidil for temple regrowth, noting slow but steady results. Despite some negative comments, he received support and encouragement from others, with advice to start treatment early for best results.

      community Gains or growth? Three months in

      in Is this regrowth?  146 upvotes 1 year ago
      The user is using topical minoxidil twice daily for hair regrowth and is hesitant to use finasteride due to concerns about hormonal effects. The conversation includes mixed opinions on the effectiveness of the treatment and suggestions to use a DHT blocker for better results.

      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 11 months ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community RU-58841 without finassteride?

      in Treatment  6 upvotes 11 months ago
      RU58841 is used without finasteride by some due to side effects, with mixed results. Users report combining RU58841 with minoxidil and adjusting finasteride doses to manage hair loss.

      community Has Anyone Gotten Results With TH16?

      in Product  5 upvotes 3 years ago
      The conversation discusses using TH16, a topical melatonin with resveratrol, and stemoxydine for hair maintenance, avoiding finasteride and minoxidil due to side effects. The user is considering a low-dose topical finasteride despite sensitivity.

      community Best source for pyrilutamide EU

      in Product  4 upvotes 2 months ago
      The conversation discusses hair loss treatments, specifically mentioning pyrilutamide, minoxidil, and finasteride. The consensus suggests starting treatment early, with finasteride being a preferred option.

      community 39m 1.1mg finasteride 3mg oral minoxidil

      in Progress Pictures  17 upvotes 2 years ago
      A user shared their progress using 1.1mg oral finasteride and 3mg oral minoxidil since January 2024, noting significant improvement without side effects. They previously had an allergic reaction to topical treatments.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  24 upvotes 6 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community Is this hierarchy of topical anti androgens accurate?

      in Ketoconazole  7 upvotes 4 years ago
      User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 3 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community 3 months of 1 mg finasteride and 5 mg minoxidil (oral)

      in Progress Pictures 4 years ago
      A user's progress with hair regrowth after 3 months of using 1 mg finasteride and 5 mg minoxidil orally, despite some skepticism from other users. The user reports having low blood pressure and feeling fatigued as side effects, but others suggest switching to topical minoxidil for better results with less risk.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 year ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.