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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Amazing progress after 4 months but way too expensive

      in Progress Pictures  3 upvotes 1 year ago
      The user experienced significant hair improvement using a costly treatment involving a tincture and micro needling. They are seeking cheaper alternatives, with suggestions including finasteride, dutasteride, and minoxidil as effective options.

      community Natural methods only. Gains or Nah?

      in Is this regrowth? 7 months ago
      The user is attempting to regrow hair using natural methods like microneedling, rosemary oil, and capsaicin tincture, avoiding medications like finasteride and minoxidil due to past health issues. Feedback suggests these methods are ineffective, with many recommending shaving or considering a hair system instead.

      community How does one use topical melatonin?

      in Treatment  3 upvotes 2 years ago
      The conversation is about using melatonin for hair loss treatment, questioning whether to mix oral melatonin with minoxidil or to apply a melatonin tincture directly to the scalp.

      community GT20029 - Promising phase II results

      in Research/Science  15 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 4 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  157 upvotes 1 year ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

      community Alternatives to Minox for pet safety

      in Minoxidil  2 upvotes 5 months ago
      The conversation discusses alternatives to minoxidil for beard growth, focusing on a product called Neofollics Beard Growth Serum, which claims to be effective without using minoxidil. Concerns are raised about its ingredients and effectiveness, especially considering pet safety.

      community Does pyri/kx826 degrade in exposure to bathroom light?

      in Treatment  5 upvotes 1 year ago
      The conversation discusses concerns about RU58841 degrading when exposed to light and transferring pyri to a dark glass bottle to prevent this. The user keeps the pyri out for only two minutes before storing it in a dark place.

      community Recommendations for topical saw palmetto / pumpkin seed oil product

      in Treatment  2 upvotes 5 years ago
      The user is seeking recommendations for topical saw palmetto and pumpkin seed oil products to treat early male pattern baldness and is considering different options available online. They are specifically asking which saw palmetto product to choose between two provided links.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 6 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Hair Regrowth with Novel Hemp Extract - anyone seen this??

      in Research/Science  18 upvotes 1 year ago
      A user discusses a novel hemp extract for hair regrowth, which showed superior results to finasteride and minoxidil. The formula includes CBD, CBDV, THCV, delta 9 THC, cannabigerol, and cannabinol, combined with menthol, peppermint oil, ethanol, Emu oil, HFA 134A propellant, and dimethicone.

      community 23 year old male 1mg fin everyday

      in Progress Pictures  41 upvotes 2 years ago
      A 23-year-old male shared his 4-month progress using 1mg finasteride daily, along with B-12 and D3+K2 supplements, to address hair loss. He sought feedback on using generic finasteride and shared his journey to regain confidence.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2263 upvotes 11 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.