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      community PP405 mechanism question - looking for discussion

      in Treatment  7 upvotes 1 week ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Tropical growth stimulants other than minoxidil

      in Treatment  9 upvotes 1 year ago
      The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.
      TresslessGPT is now available for free

      community TresslessGPT is now available for free

      in General  386 upvotes 1 year ago
      Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 2 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Baby hairs growing with 0.33g of fin every other day!

      in Progress Pictures  51 upvotes 1 year ago
      A user reports hair regrowth at the temples after starting 0.33g of finasteride every other day in January, combined with weekly microneedling sessions. They experienced sexual side effects at higher doses, which improved with a lower dose and supplements like broccoli extract and l-citrulline.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 7 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

      in Research/Science  133 upvotes 6 months ago
      A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.

      community 6 months progress, topical Fin/Min

      in Is this regrowth?  152 upvotes 1 year ago
      The post discusses a user's 6-month progress using topical finasteride (0.08%) and minoxidil (5%) once a day, combined with scalp micropigmentation (SMP). The user hopes for improved hair growth as they let their hair grow out.

      community Upcoming and current hair growth stimulants (2026)

      in Research/Science  90 upvotes 1 month ago
      The conversation discusses various hair growth treatments, including topical and oral minoxidil, microneedling, LLLT, PRP, exosomes, latanoprost, copper peptides, and upcoming treatments like PP405 and Vdphl01. It also covers managing side effects of minoxidil, such as dry scalp, and mentions the use of dutasteride and finasteride for hair loss.

      community That's some regrowth, I guess. [M31]

      in Is this regrowth?  24 upvotes 1 year ago
      The post and conversation are about a user experiencing hair regrowth after using Minoxidil 5% twice daily, topical finasteride 0.05% once daily, weekly microneedling, and ketoconazole shampoo. Other users noted visible progress and shared their own treatment experiences.

      community Regrowth Update on Crown/Vertex

      in Progress Pictures  18 upvotes 1 year ago
      User shared progress pictures of hair regrowth on the crown/vertex after a transplant and using finasteride, Minoxidil foam, and a dermapen. They hope to fully regrow or increase density in the crown area.

      community Has anyone tried Topical oxytocin?

      in Treatment 2 years ago
      A user reported less hair shedding using melatonin spray and is considering trying topical oxytocin or estrogel for hair growth, but is concerned about potential side effects like breast development. Topical oxytocin has been found to promote hair growth by increasing growth factors.
      Regrowth or I am trippin?

      community Regrowth or I am trippin?

      in Journals / Progress Pictures  46 upvotes 1 year ago
      The user has been taking 1 mg of finasteride daily for four months and is questioning if they are experiencing hair regrowth, as suggested by their barber. Another user suggests taking better photos to assess the crown area more clearly.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  32 upvotes 9 months ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community Is this regrowth or vellus hairs?

      in Is this regrowth?  1 upvotes 1 year ago
      A user with long-term hair loss has been using topical minoxidil, finasteride, RU58841, ketoconazole, and dermastamping for 8 months. They are unsure if the new hairs are miniaturized or vellus.

      community Is this regrowth? Or is hair just longer

      in Is this regrowth?  6 upvotes 2 years ago
      The user has been using 15% minoxidil, rosemary oil, peppermint oil, and bi estro cream for hair loss and is noticing baby hairs but is unsure if this is new hair growth or just existing hair getting longer.

      community You want growth but don't use a Dermaroller

      in Microneedling  95 upvotes 5 months ago
      Using a dermaroller can enhance hair regrowth, especially when combined with minoxidil, and is recommended at depths of 0.75-1.5mm weekly. Microneedling boosts absorption and blood flow, and red light therapy is also being considered for hair growth.

      community Is this Regrowth? 4 months fin+minox + dermarolling

      in Is this regrowth?  46 upvotes 7 months ago
      The user has been using finasteride, minoxidil, dermarolling, and keto shampoo for hair regrowth, showing positive results after four months. Some users suggest adding tretinoin cream for better absorption, and there's a debate on whether finasteride should be taken at night.

      community 24 M. Is this hair growth on my temples. Left picture is taken on october. Right is my current hair. I’m not using any meds or anything. Just microneedling and some essential oils

      in Microneedling  7 upvotes 4 years ago
      The conversation is about a 24-year-old using microneedling and essential oils, specifically neo hair lotion, to promote hair growth on the temples. The user reports seeing hair growth without using medications, using a 0.5 mm needle roller and planning to switch to a 1.0 mm needle.

      community Little hairs on temples, is it a good sign?

      in Is this regrowth?  425 upvotes 10 months ago
      The conversation discusses hair regrowth, with users sharing experiences and advice on using finasteride, minoxidil, and dermarolling to stimulate hair growth. Many users report seeing small hairs, which they consider a positive sign, though opinions vary on whether these hairs will develop into thicker, terminal hairs.

      community 4 month topical fin/min progress pics

      in Progress Pictures  622 upvotes 11 months ago
      A user experienced significant hair regrowth after 4 months using topical finasteride and minoxidil, along with dermastamping and biotin supplements, without side effects. They are not considering a hair transplant due to the success of this regimen.