Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.
RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.
The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.
Some individuals experience hair loss despite using treatments like 2.5 mg dutasteride, finasteride, and minoxidil, suggesting sensitivity to DHT or other factors. Various treatments and lifestyle changes are discussed, but results vary, and some consider hair transplants or other solutions.
The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.
The user is starting dutasteride mesotherapy and seeks information on checking serum DHTlevels in Germany. They previously tried finasteride but experienced unpleasant side effects.
The conversation discusses the effectiveness of different doses of Dutasteride (Dut) in reducing scalp DHTlevels. It suggests that 1mg and 1.5mg doses would reduce scalp DHT by amounts between 51% and 79%.
User experienced good results with topical finasteride, noting reduced DHT and increased testosterone. They plan to revert to a lower dosage after observing slight libido reduction.
The conversation discusses hair loss and the impact of testosterone and DHTlevels, with suggestions to monitor these levels and consider vitamin D supplementation. Treatments mentioned include finasteride and possibly minoxidil.
The conversation is about the effects of green tea on DHTlevels and its impact on hair loss. It concludes that natural remedies like green tea are less effective than hair loss drugs such as Minoxidil, finasteride, and RU58841.
The user has been taking dutasteride for 8 months and finasteride before that, with normal DHTlevels but high estradiol and prolactin, leading to sexual side effects. The user is disappointed with these results.
Curcumin, found in turmeric, may reduce DHTlevels and hair loss, similar to finasteride, but without its side effects. However, natural DHT blockers are generally considered too weak to make a significant difference in hair loss.
A user reported a significant reduction in DHTlevels after 3 months of taking 1mg/day oral finasteride, along with using minoxidil foam, microneedling, and Nutrafol vitamins. They hope this will lead to hair growth and less shedding.
The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.
The user lost ground on oral finasteride and plans to switch to topical finasteride/minoxidil and microneedling. They are curious if topical treatments are more effective than oral ones.
The user discussed switching from RU58841 with Minoxidil to Finasteride due to cost, noting better physical feelings and hair growth with RU58841. They are considering returning to RU58841 and checking DHTlevels after a month.
Creatine may increase DHTlevels, potentially affecting hair loss, but evidence is mostly anecdotal. A study to explore this was withdrawn due to funding issues.
Dutasteride can cause hair shedding even with suppressed testosterone levels due to previous damage from DHT. Hair shedding is often a sign of damaged hair being replaced by healthier growth.
A user reported using a topical hair loss treatment containing Minoxidil, Dutasteride, and other ingredients, noting a significant drop in DHTlevels and a smaller decrease in testosterone after three months. They also mentioned microneedling, feeling fine with unchanged or increased libido, and taking Cialis as a preventative measure for performance issues.
Blocking DHT is not a complete solution for hair loss; instead, altering the scalp's response to DHT may be more effective. Topical finasteride and minoxidil are current treatments, but future approaches may involve bioengineering, gene therapy, and inflammation control.
The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.
27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.
The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.
A 16-year-old is experiencing hair loss and is using minoxidil, finasteride, and plans to add RU58841, while considering other treatments like MK-677 and microneedling. Concerns are raised about the potential impact of these treatments on puberty and development.
Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.
A user on dutasteride for hair loss noticed hair regrowth on their head but a significant reduction in body hair growth. They plan to switch to finasteride and dutasteride and are considering testosterone replacement therapy but are concerned about its effects on hair growth.
The impact of creatine on DHTlevels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHTlevels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.
The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.