Pyrilutamide (KX-826) is discussed as an anti-androgen treatment for hair loss, with mixed user experiences. Some users report no results, while others find it mildly effective.
The conversation discusses starting finasteride 1mg daily for hair loss and mentions a high baseline DHT level. Users comment on the unusually high DHT level and its potential causes.
The user experienced excessive scalp oiliness and high testosterone levels after switching from finasteride to dutasteride. They plan to manage their condition with finasteride and are considering spironolactone to reduce testosterone and restore dry skin.
A 22-year-old with advanced diffuse thinning is considering oral dutasteride after stopping finasteride due to side effects like brain fog and testicular pain. They are also contemplating a hair transplant combined with oral dutasteride and topical finasteride, noting a thick donor area.
Starting hair loss treatment early is crucial for better results. Dutasteride and finasteride are effective, with dutasteride often considered superior, while oral minoxidil shows better gains than topical.
The conversation is about comparing the effectiveness of 5% RU58841 and 0.5% pyrilutamide for hair loss treatment. The user is asking if the higher concentration of RU58841 makes it stronger than the lower dose of pyrilutamide.
The user improved their hair loss from a Norwood scale 2.5/3 to 1.5/2 using treatments including 2.5 mg dutasteride, RU58841, 15 mg oral minoxidil, isoflavones, NAC, pumpkin seed oil, NAD+, and Vipelin, but still experiences temple recession. Other users expressed concern over the high dosages of oral minoxidil and dutasteride.
A user is considering an extensive hair loss treatment regimen including oral dutasteride, oral minoxidil, topical finasteride, tretinoin, microneedling, keto shampoo, laser comb, and PRP injections. Suggestions include simplifying the routine, possibly increasing minoxidil dosage, and considering alternatives like RU58841, while cautioning against using estrogen due to potential side effects.
The conversation discusses using minoxidil with microneedling and considering tretinoin to enhance hair growth, especially for those who are weak responders to minoxidil. It also explores the potential of using tazarotene, a stronger retinoid, to boost minoxidil's effectiveness and addresses purchasing tretinoin from Germany.
User on 100mg spiro and oral minox for 2 years, now switching to dut due to low testosterone. Asks if tapering spiro is necessary or can stop immediately.
The conversation discusses a hair loss treatment regimen that includes a topical spray with finasteride and minoxidil, tretinoin, and using a Derminator (microneedling device) at 1.25mm depth every 5-6 days. The user reports positive results after 90 days and plans to continue the treatment, with others commenting on the process and potential outcomes.
A 25-year-old switched from finasteride to dutasteride, experiencing significant hair regrowth and improved hair quality after 6 months, taking it three times a week. The user stopped finasteride entirely, citing dutasteride's longer half-life as more effective.
The user experienced initial success with topical finasteride 0.025% and melatonin but noticed rapid hair thinning after three months. They are considering switching to a higher dose of topical finasteride or oral finasteride, as advised by others, while being cautious about potential side effects.
A user had a hair transplant 16 years ago and lost hair after stopping finasteride. They're now using a combination of treatments including oral dutasteride, topical and oral minoxidil, Pyrilutamide, and microneedling, and have seen improved density but are unsure if it's enough to grow their hair out. They also had a bad experience with scalp micropigmentation (SMP) and are considering redoing it.
Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.
The user switched from finasteride to dutasteride for hair loss and noticed elevated cholesterol levels, questioning if dutasteride caused this change. They also take Vitamin D, biotin, magnesium, ginkgo biloba, omega-3, and NAC, and are concerned about the impact of these supplements and their health on cholesterol levels.
Channing Tatum's hair loss and whether he accepted baldness or had a hair transplant. Users share experiences with finasteride and hair transplants, and discuss the importance of hair maintenance with age.
Tretinoin can make minoxidil more effective for hair loss treatment, but some users did not see improved hair density with this combination and had better results with dutasteride.
The user reported significant hair improvement over 15 months using dutasteride, minoxidil (oral and topical), RU58841, ketoconazole, and microneedling. They are considering a hair transplant in 4-6 months.
The conversation is about someone's progress with hair loss treatment using a combination of topical finasteride and minoxidil, and dermastamping once a week. They are considering increasing the dermastamp needle size from 1.25mm to 1.5mm.
User started balding at 16 and began treatment at 18, using RU58841, minoxidil, derma rolling, and peptides. After 6 months, they experienced significant hair regrowth and are happy with the results.
The conversation discusses the potential availability of a new hair loss treatment, GT20029, on the grey market, with users suggesting it could be within a year but advising against using grey market products due to safety concerns and complexity of the drug.
The post humorously discusses an exaggerated hair loss treatment regimen including minoxidil, finasteride, microneedling, and "demon blood." Replies joke about the regimen and suggest alternative sources for "demon blood."
The user had a hair transplant in 2021 with 1600 grafts and is currently using finasteride, minoxidil, biotin, and collagen. They are considering another transplant in Turkey to address a bald spot and improve coverage in the front and middle.
The conversation discusses hair loss treatments, including topical and oral minoxidil, finasteride, RU58841, and microneedling. Users suggest adding oral dutasteride or finasteride for more effective results.
RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.
The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.
The conversation discusses the safety of taking multivitamins and zinc tablets while using finasteride. Users share experiences with additional supplements like vitamin D3, K2, biotin, and oral minoxidil.
A human trial involving the use of Verteporfin as a treatment for hair loss, which has been ongoing for 119 days with an update on its progress. Treatments such as Minoxidil, Finasteride and RU58841 have also been discussed.