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      community Patent for topical resveratrol and melatonin for AGA

       5 upvotes 6 years ago
      The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.

      community EU topical melatonin recommendations?

      in Treatment  6 upvotes 4 months ago
      The conversation discusses recommendations for using topical melatonin for hair loss treatment. It also mentions Minoxidil, finasteride, and RU58841 as other treatments.

      community Vitamin D3 Supplement for Hair

      in Chat  6 upvotes 2 years ago
      The conversation discusses recommendations for Vitamin D3 supplements for hair health. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Supplementation increasing T levels

      in Treatment  5 upvotes 4 years ago
      The conversation is about using finasteride for hair loss and considering supplements like ginseng or ashwagandha to boost testosterone levels. Concerns are raised about potential negative effects on hair due to increased DHT conversion, and it's suggested that natural testosterone boosters may not significantly impact those with already high testosterone levels.
      Low DHT, because of saw palmetto? (Foligain supplement)

      community Low DHT, because of saw palmetto? (Foligain supplement)

      in Finasteride  52 upvotes 6 months ago
      The user is concerned about low DHT levels due to using saw palmetto in Foligain supplements and is considering trying finasteride. They seek advice on whether finasteride will also lower DHT and how to manage DHT levels.

      community The solution for Topical Fin non responders?

      in Finasteride/Dutasteride  1 upvotes 3 months ago
      The user is considering using tretinoin with topical finasteride due to poor absorption and side effects from oral finasteride. They are also contemplating switching to topical dutasteride, while others suggest trying oral minoxidil or lower oral doses.

      community Non responsive diffuse thinning

      in Progress Pictures  9 upvotes 7 months ago
      The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

      community Huge hair shedding on Astaxanthin.

      in Treatment  2 upvotes 1 month ago
      Astaxanthin may cause increased hair shedding, affecting even transplanted hair and eyebrows. The user has tried various treatments for androgenic alopecia, including minoxidil, finasteride, and RU58841.

      community Mineral deficiencies vs MPB vs Thyroid

      in Chat  8 upvotes 1 year ago
      The user experienced hair improvement using a topical finasteride, minoxidil, and tretinoin combo, along with supplements like zinc, copper, magnesium, vitamin D3, K2, iodine, and boron. They believe these changes are due to addressing mineral deficiencies and possibly thyroid issues, despite skepticism from others.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Thoughts on these and similar other products?

      in Chat  4 upvotes 1 year ago
      The conversation discusses the effectiveness of DHT blockers for hair loss, questioning if they are just vitamins or truly effective. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Is this solution unnecessarily aggresive?

      in Product  2 upvotes 4 months ago
      The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoic acid, and procapil. Users suggest minoxidil with tretinoin and a 5-alpha reductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.

      community Lab results from actifolic RU58841

      in Product  39 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

      community Thoughts on my Topical and Oral concept idea ?

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice on improving their hair loss treatment regimen, considering changes to their topical solution, and is curious about others' daily routines and recommendations for medications and supplements. They are contemplating switching Tretinoin for Tazarotene, Latanoprost for Bimatoprost, and possibly adding Alfatradiol, Topical Melatonin, or a topical androgen receptor antagonist.

      community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

      in Research/Science  2 upvotes 3 months ago
      The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

      community Is there an improvement? Zinc, biotin, and D3

      in Is this regrowth?  7 upvotes 3 years ago
      The conversation discusses hair regrowth improvement due to zinc, biotin, and D3 supplements, highlighting that hair loss can result from deficiencies, not just androgenetic alopecia. The user emphasizes that treatments like finasteride are not the only solutions.

      community What's your opinion on this type of supplements?

      in Product 10 months ago
      The conversation discusses skepticism about DHT blocker supplements for hair loss, with many users recommending proven treatments like finasteride and minoxidil instead. Some users shared personal experiences with alternative treatments like beta-sitosterol and saw palmetto, noting side effects and limited effectiveness.

      community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

      in Research/Science  136 upvotes 9 months ago
      Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 9 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 1 year ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.