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      community Should we give up on Breezula?

      in Research/Science  10 upvotes 4 months ago
      Breezula's potential as a hair loss treatment is debated, with some seeing promise despite delays, while others suggest alternatives like Pyrilutamide. Breezula is compared to topical finasteride, with hopes for a better side effect profile.

      community Minoxidil works amazingly, you just need to give it time.

      in Minoxidil  326 upvotes 4 months ago
      Minoxidil can effectively promote hair regrowth with consistent use, but results differ among individuals. Some recommend combining it with finasteride for better long-term results, though OP chooses to use only minoxidil and accepts the possibility of going bald.

      community Topical Dutasteride usage plan + build up prevention

      in Finasteride/Dutasteride  8 upvotes 4 months ago
      The conversation discusses using a 0.03% topical Dutasteride solution for hair loss, as it may be more effective than Finasteride with fewer systemic side effects. OP plans to apply it daily for 100 days, then reduce frequency, due to past negative cognitive effects from oral treatments.

      community Can I get an honest rating of my «Natural Stack?

      in Treatment 4 months ago
      The conversation discusses hair loss treatments, focusing on a "natural stack" including minoxidil, microneedling, a laser helmet, saw palmetto, ketoconazole shampoo, and supplements. Many users suggest adding finasteride or dutasteride for better results, as natural methods alone may not effectively block DHT.

      community can someone help me identify these pls

      in Treatment 4 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 4 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community 2% Ketoconazole/Nizoral Daily?

      in Ketoconazole  11 upvotes 4 months ago
      Using 2% ketoconazole daily can dry out the scalp; 1-2 times a week is recommended. Combining ketoconazole with treatments like minoxidil, alfatradiol, and fluridil can help manage hair loss effectively.

      community Why take Dut only once a week?

      in Finasteride/Dutasteride  28 upvotes 4 months ago
      The conversation discusses using dutasteride once a week to boost finasteride's effectiveness in treating hair loss, with some users reporting fewer side effects and cost savings. Others share experiences with different dosages and combinations, including minoxidil and topical treatments, to find a balance between effectiveness and side effects.

      community Results after 11 months of 2.5 Mg Oral Minoxidil and 0.5 Mg Dutasteride

      in Progress Pictures  304 upvotes 4 months ago
      The user shared progress after 11 months of using 2.5 mg oral Minoxidil and 0.5 mg Dutasteride for hair loss, expressing satisfaction but considering a future hair transplant. Other users suggested additional treatments like Latanoprost and debated the effectiveness of hair systems versus medication, with some recommending a buzz cut or hair transplant for better results.

      community Why you may be taking Dutasteride wrong

      in Finasteride/Dutasteride  63 upvotes 5 months ago
      Dutasteride is more effective than finasteride for hair loss, with optimal dosing at 0.5mg once or twice a week to minimize side effects. Topical application may further reduce side effects while effectively lowering scalp DHT.

      community 4 months topical fin and min. So far so good.

      in Is this regrowth?  146 upvotes 5 months ago
      A 44-year-old user experienced hair regrowth using a topical spray combining 0.3% finasteride and 7% minoxidil after switching from oral finasteride due to side effects. The user reported noticeable improvements in hair thickness after four months without any side effects from the topical treatment.

      community Hairline slowly coming back from the dead 💀

      in Is this regrowth?  510 upvotes 5 months ago
      A user experienced positive hair regrowth using oral and topical minoxidil, oral dutasteride, microneedling, and supplements. They noted improved hairline and temple density with minor side effects like a few forehead pimples.

      community Trying intermittent Dutasteride (0.5mg every 5-6 days)

      in Basic Questions  165 upvotes 5 months ago
      A 22-year-old male experienced hair regrowth using an intermittent Dutasteride regimen, oral and topical Minoxidil, FolliHair AM/PM, and Salicia KT shampoo. He stopped Dutasteride due to side effects like dry eyes and skin, but noticed increased hair shedding after stopping.

      community 6 Months on Oral Fin + Oral Minoxidil

      in Progress Pictures  866 upvotes 5 months ago
      A user shared their 6-month progress using oral finasteride and oral minoxidil for hair loss, reporting significant improvements with minimal side effects, such as slight erectile dysfunction that resolved. Other users discussed their experiences, concerns about side effects, and the effectiveness of these treatments.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 6 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community 9 month update - 0.25mg finasteride only daily (reposted w updated pics)

      in Progress Pictures  34 upvotes 6 months ago
      A user shared a 9-month update on using 0.25mg finasteride daily for hair maintenance, reporting no significant side effects and considering whether to add other treatments like a dermastamp or ketoconazole. The user has not used minoxidil, believes it's unnecessary unless hair loss is severe, and occasionally takes biotin supplements.

      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  12 upvotes 6 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 6 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community Progress - 9 months oral minoxidil 2.5 mg & 4 months oral finasteride 1 mg

      in Progress Pictures  8 upvotes 6 months ago
      The user has been using oral minoxidil 2.5 mg for 9 months and oral finasteride 1 mg for 4 months, along with microneedling, and has noticed more baby hairs and longer eyelashes but no extra overall thickness. They are considering increasing the minoxidil dose but are concerned about safety due to potential side effects.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 6 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community Purchasing and Shipping Alpecin DMG to the United States.

      in Product  3 upvotes 6 months ago
      A user is seeking help to purchase and ship Alpecin DMG to the United States due to issues with eBay sellers. They prefer Alpecin DMG over minoxidil because of concerns about minoxidil's effects on insulin production, as they have diabetes.