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GlossaryTopical Treatments

medications applied directly to the skin or scalp

Topical treatments, also known as topical agents or topical medications, are medications applied directly to a specific area of the skin or scalp to treat localized conditions. These treatments can include creams, gels, ointments, and lotions, and are commonly used for conditions like alopecia, psoriasis, and eczema, delivering active ingredients directly to the affected area to minimize systemic side effects.

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community My progress with various products and without oral fin or oral dut on 17 months

in Progress Pictures 62 upvotes 10 months ago

The user shared their hair loss treatment progress using topical products like exosomes, fluridil, Kx826, and topical dutasteride, avoiding oral finasteride and dutasteride due to side effects. They found exosomes from Creative Biolabs most effective and also used topical probiotics, noting improvements without significant side effects.

community What is the ultimate hair regrowth protocol

in Treatment 28 upvotes 8 months ago

The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

community M29 - 4 YEARS on Dutasteride - almost no progress

in Chat 6 upvotes 2 months ago

The user has been on a comprehensive hair loss treatment regimen for four years, including Dutasteride, topical and oral Minoxidil, and various other treatments, but has seen little progress and is considering a hair transplant. Despite trying multiple therapies, including PRP and exosome injections, the user is still experiencing hair thinning and is hesitant about trying peptides due to potential cancer risks.

community Is anyone on topical spironolactone, or has anyone tried this?

in Treatment 3 upvotes 6 days ago

Topical spironolactone is discussed as a potential hair loss treatment for those who can't tolerate finasteride, with some users noting varied results and side effects. Alternatives like laser caps are also mentioned.

community Why is nobody talking about topical Spironolactone?

in Chat 7 upvotes 6 days ago

Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

community Topical minoxidil on scalp causing dry skin on face?

in Minoxidil 2 upvotes 1 week ago

The user started using 5% liquid minoxidil on their scalp and noticed increased facial dryness and faster facial hair growth. They plan to reduce the application to once a day to see if it helps with the dryness.

community Topical min and dermarolling with seborrheic dermatitis

in Minoxidil 3 upvotes 1 week ago

The user is managing hair loss with oral finasteride, recently switching to dutasteride, and topical minoxidil, but faces challenges due to seborrheic dermatitis. They seek advice on effective regrowth methods that don't worsen their condition, with suggestions including various shampoos like Vichy Dercos and ketoconazole.

community Topical Fin/Min - 3 Month Progress

in Progress Pictures 11 upvotes 1 week ago

The user applied topical minoxidil and finasteride daily for 3 months and noticed progress in hair growth. Another user recommended collagen for hair growth and other benefits.

community Topical finasteride and minoxidil 2 months treatment update

in Progress Pictures 5 upvotes 1 week ago

The user shared a 2-month progress update using topical finasteride and minoxidil for hair loss. The conversation included comments on the user's appearance and potential side effects.

community Topical fin/minox + nizo shampoo and microneedling

in Treatment 1 upvotes 2 weeks ago

The user is using topical finasteride, minoxidil, nizoral shampoo, and microneedling for hair regrowth but hasn't seen results after 2-3 weeks. They added tretinoin to their routine and are advised to wait a few months for potential changes.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

in Research/Science 55 upvotes 3 weeks ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Is Topical Finasteride Effective for My Receding Hairline?

in Basic Questions 16 upvotes 3 weeks ago

Topical finasteride may help maintain and potentially regrow a receding hairline, but results vary. Combining it with minoxidil and microneedling could enhance effectiveness, with noticeable changes taking several months.

community Topical serum made from monounsaturated fatty acids that triggered rapid hair growth in mice within 20 days

in Research/Science 443 upvotes 3 weeks ago

A topical serum made from monounsaturated fatty acids showed rapid hair growth in mice within 20 days, but it remains experimental for humans. Users humorously discussed the frequent success of hair growth treatments in mice and expressed skepticism about translating these results to humans.

community Thoughts on topical cetirizine for AGA?

in Treatment 3 upvotes 1 month ago

Topical 1% cetirizine is more effective for hair growth than 10 mg oral cetirizine. It can be ordered online from specific hair loss companies.

community topical exosomes - experimenting

in Treatment 1 upvotes 1 month ago

The conversation is about experimenting with topical exosomes for hair loss treatment, alongside microneedling, Happy Head's gel-like topical, and Ordinary's hair serum. The user also mentions the availability of treatments like latanoprost and Redensyl.

community Topical Treatments and how would they work in a single compound

in Treatments 46 upvotes 1 month ago

A topical treatment called 1961, containing multiple products, is discussed for its compatibility with finasteride. It is suggested that 1961 does not negatively affect finasteride's effectiveness and may even enhance its absorption.

community Topical Treatment Progress

in Journals / Progress Pictures 53 upvotes 1 month ago

The user reported healthier, firmer, and thicker hair follicles with minimal regrowth at the front after using Regenera Activa, topical finasteride, minoxidil, tretinoin, caffeine solution, and vitamin D supplements. Hair loss has stabilized with no side effects.

community Topical finasteride (P-3074) inhibits scalp DHT up to 70%

in Finasteride/Dutasteride 20 upvotes 1 month ago

Topical finasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.

community Topical RU58841, which brand available in Europe with a low systemic absorption ?

in Treatment 3 upvotes 1 month ago

Topical RU58841 is discussed for hair loss treatment, with a focus on brands available in Europe that have low systemic absorption. Users suggest mixing your own solution to control vehicle and dosage, and mention different brands like Actifolic and Biolabshop.

community Topical Serenoa? Anyone tried it?

in Treatment 2 upvotes 1 month ago

The conversation discusses using topical serenoa oil, a natural anti-DHT treatment, for hair loss. It is considered less effective than finasteride and dutasteride but can be added to a routine with topical minoxidil.

community Why isn’t Topical Dutasteride the “Gold Standard”?

in Research/Science 146 upvotes 2 months ago

Topical dutasteride is more effective than finasteride for hair loss but lacks FDA approval and research, leading to less use. Users report varying effectiveness and side effects, with some preferring oral treatments.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 2 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community Topical Finasteride Pill filler

in Finasteride/Dutasteride 3 upvotes 2 months ago

Users discuss making topical finasteride solutions by dissolving crushed tablets in ethanol and propylene glycol, with concerns about residue affecting effectiveness. They also mention using minoxidil and oral finasteride, noting some hair regrowth and no side effects from topical use.

community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

in Research/Science 4 upvotes 2 months ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

community UK Options for Affordable Topical Finasteride and DIY Methods with Minoxidil?

in General 29 upvotes 2 months ago

Topical finasteride in the UK is sought after due to concerns about the strength and cost of Hims products. There is also interest in whether crushing finasteride pills into minoxidil is effective.

community Is there any topical nutrition for hair fall that can replace mesotherapy (for home use)?

in Treatment 1 upvotes 2 months ago

Topical minoxidil is effective for hair loss, while topical finasteride caused side effects like erectile dysfunction. Mesotherapy is considered stronger than home treatments like microneedling with topical nutrients.

community 2.5 years on topical finasteride (0.1% fin + 7% min): hair success and why I stopped

in Finasteride/Dutasteride 15 upvotes 2 months ago

Topical finasteride with minoxidil effectively stabilized and thickened hair but caused side effects like brain fog, reduced libido, and emotional flattening, leading to discontinuation. The user switched to a new regimen including minoxidil, KX-826, and other treatments, noting improvements in libido and vivid dreams after stopping finasteride.

community Topical Dutasteride and creatine

in Finasteride/Dutasteride 3 upvotes 3 months ago

The conversation discusses using topical dutasteride as an alternative to oral finasteride to prevent hair shedding caused by creatine supplementation. Users share experiences with finasteride, dutasteride, and creatine, noting potential side effects and effectiveness concerns with topical treatments.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 3 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community Can topical tretinoin only applied to face (not hairline) exacerbate hair loss?

in Chat 7 upvotes 3 months ago

Topical tretinoin applied to the face may exacerbate hair loss in some individuals, potentially triggering conditions like frontal fibrosing alopecia. Experiences vary, with some users reporting no impact on hair, while others experience significant hair loss.