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      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Anyone else growing tired of the finasteride wars?

      in Finasteride/Dutasteride  169 upvotes 2 years ago
      The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

      community Hair Loss Treatment Iceberg Chart

      in Satire  1378 upvotes 4 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

      community My "natural" hair care regimen--will keep updates

       4 upvotes 7 years ago
      A 25-year-old is experiencing mild hair loss and is using a regimen including scalp brushing, dermarolling, topical minoxidil, caffeine, melatonin, and a DHT-blocking shampoo. Another person shares their struggle with hair loss due to drug use and plans to start finasteride while trying to quit drugs.

      community Dutasteride is a Miracle Drug.

      in Finasteride/Dutasteride  250 upvotes 10 months ago
      Dutasteride is praised for improving skin and hair regrowth, with fewer side effects than finasteride. Users report mixed results on shedding and regrowth, with some experiencing enhanced libido and skin quality.

      community Topical Finasteride in India??

      in Finasteride/Dutasteride  7 upvotes 2 years ago
      The post expresses frustration over the unavailability of pure topical finasteride in India despite the developed pharma industry. The user seeks advice on making it at home and its effectiveness.

      community Homemade topical spironolactone

      in Research/Science  25 upvotes 3 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

      community Topical Dutasteride and creatine

      in Finasteride/Dutasteride  3 upvotes 5 months ago
      The conversation discusses using topical dutasteride as an alternative to oral finasteride to prevent hair shedding caused by creatine supplementation. Users share experiences with finasteride, dutasteride, and creatine, noting potential side effects and effectiveness concerns with topical treatments.

      community Topical solutions combining minoxidil and finasteride?

      in Treatment  2 upvotes 10 months ago
      A user is seeking advice on creating a topical solution combining minoxidil, finasteride, and tretinoin for hair loss, and is unsure about optimal concentrations and availability. Another user shares their custom formula with tretinoin 0.015%, finasteride 0.025%, and minoxidil 5%, and mentions taking oral dutasteride 0.25mg daily.

      community Topical minoxidil 3 months results

      in Progress Pictures  624 upvotes 3 years ago
      This conversation is about a user named "mr_mime125" who experienced results from using topical finasteride (0.1%) and minoxidil (5%) solution 1.5 ml twice a day for the first two months followed by just minoxidil (5%) 1 ml once a day in the last month, resulting in a drastic improvement to their hairline. Other users discussed their progress while asking questions and offering encouragement.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 4 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Topical fin 0.025%, min 5% - 2,5 months progress

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.

      community Topical finasteride carrier/vehicle

      in Finasteride  135 upvotes 1 year ago
      The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

      community 4 months topical minoxidil + 2 months finasteride

      in Minoxidil  132 upvotes 1 year ago
      Topical minoxidil and oral finasteride are effectively promoting hair growth with minimal side effects, such as no impact on sex drive. Users report positive results and reduced hair shedding, with some using a combination of topical foam containing both minoxidil and finasteride.

      community Topical Dutasteride & Microneedling Works

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.