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      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Amazing progress after 4 months but way too expensive

      in Progress Pictures  3 upvotes 1 year ago
      The user experienced significant hair improvement using a costly treatment involving a tincture and micro needling. They are seeking cheaper alternatives, with suggestions including finasteride, dutasteride, and minoxidil as effective options.

      community 14-Month Update - FUE Hair Transplant

      in Update  977 upvotes 4 years ago
      A 14-month update on a FUE hair transplant, and the effects of male pattern baldness. People discussed products such as Minoxidil, finasteride, Kerastase Chronologiste shampoo and care oil, and RU58841 to help treat hair loss.

      community Regrowth after 9 months of DHT blockers, and 6 months of HRT

      in Transgender  24 upvotes 7 months ago
      A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

      community Alternative keto shampoo to nizoral?

      in Ketoconazole  4 upvotes 1 year ago
      The conversation is about finding an alternative ketoconazole shampoo to Nizoral due to its strong smell, with suggestions including Intelligent shampoo and Sons brand. The discussion also touches on the effectiveness of ketoconazole for dandruff and hair loss, with some users recommending prescription options for higher concentrations.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  145 upvotes 1 year ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community How do we only have two treatments to combat hair loss at this point in time?

      in Chat  211 upvotes 2 years ago
      The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

      community Solo use of Pyrilutamide: UPDATE

      in Update  45 upvotes 3 years ago
      A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

      community 2.5 years 1mg finasteride daily

      in Progress Pictures  4864 upvotes 5 months ago
      Significant hair regrowth was achieved after 2.5 years of taking 1 mg finasteride daily, without using minoxidil or microneedling. Minor side effects included a slightly thinner beard and longer time to finish during sex.

      community Most promising cures for baldness as of May 2026

      in Treatment  56 upvotes 4 weeks ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community When is the cure gonna drop , how much more time

      in Research/Science  112 upvotes 3 months ago
      There is no imminent cure for hair loss, but treatments like Minoxidil, Finasteride, and new drugs such as KX-826, GT-20029, and PP405 are being explored. Current solutions focus on slowing hair loss and stimulating growth, with hopes for better options in the future.

      community Bee venom better than minoxidil?

      in Research/Science  1061 upvotes 6 months ago
      Bee venom at 0.001% concentration was more effective than 2% minoxidil in promoting hair growth in mice, possibly due to increased growth factors and reduced inflammation. Caution is advised due to potential allergic reactions and the reliance on animal data.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 9 months ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community 5 year update on Finasteride and Minoxidil

      in Progress Pictures  421 upvotes 1 year ago
      The user has used finasteride and minoxidil for five years to slow hair loss but hasn't seen regrowth. They are considering increasing finasteride dosage, switching to dutasteride, and exploring microneedling and oral minoxidil.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 3 years ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community 1600 grafts (~5500 hairs) | 10 month results

      in Transplants  1669 upvotes 11 months ago
      The user received 1600 hair grafts but is dissatisfied and plans a second transplant for better coverage. They use minoxidil and finasteride and are considering adding dutasteride.

      community I want it all to end so badly. I’ve lost my 20s to this

      in Chat  73 upvotes 3 weeks ago
      A person struggling with hair loss is using treatments like dutasteride, oral minoxidil, and has had a hair transplant but remains deeply unhappy. Others suggest alternative treatments, acceptance, and focusing on other life aspects, emphasizing mental health and therapy.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2446 upvotes 5 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.