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The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

A user experienced hair shedding despite using natural remedies but saw improvement with topical finasteride and oral minoxidil. After stopping supplements like saw palmetto and pumpkin seed oil, shedding resumed, but combining them again with finasteride and minoxidil reduced shedding.

A user successfully regrew hair using oral finasteride (1mg daily for 3 years) and topical minoxidil (5% twice daily for 15 years) with no side effects. They highlighted the importance of consistency and patience, crediting finasteride for significant hair improvement.

The user has been using finasteride for three years and topical minoxidil, and while they feel they've lost some ground in the last 18 months, most responses suggest their hair looks the same or even fuller. The general consensus is that the treatments have maintained the hair well, with some users suggesting additional treatments like derma stamping or dutasteride for further improvement.

The user is struggling to obtain a finasteride prescription in France after moving there, despite previously using it alongside minoxidil, kz shampoo, and biotin supplements. They are advised to seek alternative doctors, consider telemedicine platforms, or explore topical finasteride options.

A person shared their hair regrowth journey using HIMS topical treatments with finasteride, minoxidil, hormone replacement therapy (HRT), and microneedling. They also discussed their transition as a transgender woman and the positive impact of HRT on hair recovery.

A user is starting a hair loss treatment with Minoxidil (5 mg oral and 10% topical), Dutasteride, and Zinc, and is concerned about the high dosages. Other users suggest following the dermatologist's advice, starting with topical treatments, and discussing dosage concerns with the doctor.

The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.

An 18-year-old male experiencing hair loss since 2023 is using minoxidil, microneedling, and topical finasteride. He is considering switching to oral finasteride for potentially better results.

A 22-year-old male is using 5% topical minoxidil, microneedling, saw palmetto, and biotin for hair loss with positive results but is considering switching to finasteride. Many users suggest adding finasteride for better long-term results, with some recommending online prescriptions due to local prescription challenges.

A 23-year-old male experiencing worsening hair loss has tried topical Minoxidil, Finasteride, Progesterone, Hydrocortisone butyrate, and Ketoconazole. He is considering switching to oral Finasteride due to concerns about side effects and lack of improvement.

The conversation is about a user's progress in treating hair loss using 1mg finasteride, topical minoxidil once at night, and weekly 1.5mm microneedling. The user reports significant improvement and no side effects, while others discuss their experiences and offer advice on similar treatments.

Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

A 19-year-old male experienced hair shedding after one year on dutasteride and is considering adding topical minoxidil despite scalp itching. Users suggest continuing dutasteride, maintaining a consistent hair routine, and possibly increasing minoxidil dosage.

A 23-year-old experiencing diffuse hair thinning has chosen a treatment stack including topical finasteride, a blend of rosemary, peppermint, and pumpkin seed oils, procyanidine B2 spray, ketoconazole shampoo, and scalp massages. They avoid minoxidil due to family history of side effects and oral finasteride due to high estrogen levels.

User shared 7-month hair loss progress pictures. They used Minoxidil 10% topical solution.

The user shared a one-year progress of hair regrowth using topical minoxidil and dutasteride, along with microneedling and scalp massages. They experienced significant hair growth without side effects.

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

A user shared their 5-month hair regrowth progress using 5% topical minoxidil daily, microneedling weekly, and ketoconazole shampoo twice a week. Some suggest adding finasteride to maintain results, while others commend the current regimen's effectiveness.

User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

The conversation discusses challenges in obtaining finasteride in the Netherlands and explores alternatives like natural DHT blockers and topical finasteride. Suggestions include consulting different doctors or dermatologists and considering cost-effective options like cutting higher-dose tablets.

Focus on scalp health, not just DHT suppression, is crucial for hair regrowth. Effective treatments include Hair Restoration shampoo, LLLT laser cap, microneedling, and topical finasteride.

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

A 42-year-old is using dutasteride, oral and topical minoxidil, ketoconazole, and a dermaroller for hair loss, with noticeable progress after six months. They are questioning if further gains are possible and considering stopping the dermaroller, as advised that future improvements may only involve hair thickening.

A 23-year-old shared his successful hair regrowth journey, highlighting the importance of correcting vitamin deficiencies and using oral minoxidil and finasteride, later switching to topical minoxidil. He emphasized the effectiveness of addressing basic health issues and staying consistent with treatments.

A 29-year-old shared their crown hair recovery using a daily liposomal topical solution of finasteride and minoxidil, low-level light therapy, and specific vitamins, noting significant improvement without side effects. They experienced issues with oral finasteride previously but not with the topical treatment.

The user "OP" is frustrated with hair loss despite using oral minoxidil, topical finasteride, and oral dutasteride. Other users suggest keto shampoo, lifestyle changes, and low light laser therapy.

The user experienced significant hair thinning and scalp irritation after three months of using topical finasteride. Suggestions include that shedding is normal before regrowth and switching to oral finasteride or addressing scalp inflammation might help.