The user seeks alternatives to PropyleneGlycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.
The conversation discusses two methods for making topical finasteride: using ethanol and propyleneglycol or mixing it with topical minoxidil. The focus is on solubility and absorption, with a suggestion to crush pills finely and possibly mix with minoxidil at a slightly elevated temperature.
Switching from propyleneglycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.
The conversation discusses adjusting the isopropyl alcohol, propyleneglycol, and water ratios in a topical finasteride solution for better scalp comfort and less dandruff. The user considers using 20ml IPA, 25ml PG, and 15ml water in a 60ml bottle, moving away from mixing finasteride with topical minoxidil.
The user is seeking a topical minoxidil and finasteride combination without propyleneglycol due to scalp irritation. They are looking for a supplier in the US.
The conversation discusses the pros and cons of using propyleneglycol versus ethyl alcohol in topical solutions for finasteride and minoxidil. It questions why propyleneglycol is commonly used and whether ethyl alcohol might be a better option.
The conversation discusses using topical finasteride with propyleneglycol, which causes scalp dryness or dandruff. The user also uses Nizoral, Nioxin, and DHT oil, and considers using a scalp conditioner to alleviate dryness.
The conversation discusses the best ethanol and propyleneglycol ratio for homemade topical finasteride, with a focus on absorption and drying issues. The user shares their experience using a 50% propyleneglycol, 30% ethanol, and 20% water solution, and considers adjusting the ethanol content for better results.
A user asked if olive oil can replace propyleneglycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.
A user is seeking topical versions of minoxidil and finasteride in Australia that do not contain propyleneglycol. They are looking for alternatives due to potential irritation from propyleneglycol.
A new alcohol-free, propyleneglycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.
The user is using Dutasteride and oral Minoxidil for hair regrowth and is considering adding topical Minoxidil but is allergic to propyleneglycol, which is present in the product they found. They need a solution with tretinoin that does not contain propyleneglycol.
A user is experiencing scalp flaking from a finasteride/minoxidil topical solution and considers using salicylic acid shampoo to remove propyleneglycol residue. Another user suggests trying a leave-in conditioner to address dryness and flaking.
The conversation discusses using Rogain foam as a solvent for topical finasteride due to an allergy to propyleneglycol. The foam's ingredients, including alcohol SD 40B, are considered suitable for dissolving finasteride for easier application without skin irritation.
A user made a 70/30 ethanol/propyleneglycoltopical finasteride solution but noticed chunks at the bottom. The discussion focuses on this issue with the DIY hair loss treatment.
The conversation discusses creating a DIY topical finasteride solution for someone allergic to propyleneglycol, with suggestions to use glycerin or a glycerol-based vehicle instead. The user also mentions using foam minoxidil.
The conversation is about creating a DIY topical finasteride solution using ethyl alcohol and propyleneglycol. A user suggests using a compounding pharmacy instead.
A user allergic to propyleneglycol seeks alternatives for a DIY topical finasteride solution, considering glycerin or glycerol-based vehicles. Another user suggests a recipe using propanediol, DMSO, MCT oil, and peppermint oil, incorporating minoxidil, dutasteride, and finasteride.
Different minoxidil formulations affect hair growth and side effects. Higher propyleneglycol and pH levels improve effectiveness but can cause scalp irritation.
The conversation discusses the use of ethanol and propyleneglycol (PG) in topical solutions for hair loss treatments, specifically Minoxidil. The user dislikes the texture of PG and questions the ideal ratio and necessity of PG in these solutions.
The conversation is about finding affordable topical dutasteride without propyleneglycol for hair loss treatment. Suggestions include making a DIY solution using dutasteride powder and minoxidil, with sources like Carolina Chemicals and Minoxidil Max mentioned.
Users discuss making topical finasteride solutions by dissolving crushed tablets in ethanol and propyleneglycol, with concerns about residue affecting effectiveness. They also mention using minoxidil and oral finasteride, noting some hair regrowth and no side effects from topical use.
Topical finasteride may have higher systemic absorption and lower efficacy when using a PropyleneGlycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.
The user is using a 5% minoxidil solution with low propyleneglycol and 1 mg of oral finasteride daily but is still experiencing hair shedding, especially at the temples and front. They are concerned about absorption issues and considering adding tretinoin to improve results.
A user is seeking UK-based sources for propyleneglycol and ethanol to dilute topical finasteride for hair loss treatment. They currently order from MinoxidilMax but want a faster shipping option.
Topical Minoxidil and RU58841 can make hair look brittle and thin, possibly due to the propyleneglycol in their solutions. Some users experience side effects like heart palpitations with RU58841, while others have no issues.
The conversation is about someone switching from a hair loss treatment spray with alcohol and propyleneglycol to a serum with essential oils, questioning the absorption and effectiveness of the new product. The spray and serum both contain 0.3% finasteride and 6% minoxidil.
A user in Poland created a homemade "oral topical minoxidil" using 2% topical minoxidil, propyleneglycol, and vodka due to difficulty obtaining oral minoxidil. They shared a recipe and sought feedback, emphasizing caution and safety in dosing.
The conversation is about making homemade topical finasteride by crushing pills and mixing them with ethanol and propyleneglycol or minoxidil. Users discuss sourcing options and share experiences with DIY solutions.